Channel:  Aligning Science Across Parkinson's (ASAP)

458 Articles

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Transient dopamine neuron activity precedes and encodes the vigor of contralateral movements
Mendonca, M. D., Alves da Silva, J., Hernandez, L. F., Castela, I., Obeso, J., Costa, R. M.
10.1101/2021.04.20.440527 — Posted: 2021-12-02
Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice
Schor, J. S., Gonzalez Montalvo, I., Spratt, P. W. E., Brakaj, R. J., Stansil, J. A., Bender, K. J., Nelson, A. B.
10.1101/2021.11.12.468404 — Posted: 2021-11-13
SHIP164 is a Chorein Motif Containing Lipid Transport Protein that Controls Membrane Dynamics and Traffic at the Endosome-Golgi Interface.
Hanna, M. G., Suen, P., Wu, Y., Reinisch, K. M., De Camilli, P.
10.1101/2021.11.04.467353 — Posted: 2021-11-12
Serum neurofilament light as a biomarker for prognosis in patients with newly diagnosed Parkinson disease
Vijiaratnam, N., Lawton, M., Heslegrave, A., Guo, T., Tan, M. M., Jabbari, E., Real, R., Woodside, J., Grosset, K. A., Chelban, V., Athauda, D., Girges, C., Barker, R. A., Hardy, J., Wood, N., Houlden, H., Williams, N., Ben-Shlomo, Y., Zetterberg, H., Grosset, D. G., Foltynie, T., Morris, H.
10.1101/2021.11.01.21265751 — Posted: 2021-11-02
Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons
Hwang, F.-J., Roth, R. H., Wu, Y.-W., Sun, Y., Liu, Y., Ding, J. B.
10.1101/2021.10.28.466357 — Posted: 2021-10-28
Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.
Geertsma, H. M., Suk, T. R., Ricke, K. M., Horsthuis, K., Parmasad, J.-L. A., Fisk, Z., Callaghan, S. M., Rousseaux, M. W. C.
10.1101/2021.10.13.464123 — Posted: 2021-10-14
Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis
Boland, S., Swarup, S., Ambaw, Y. A., Richards, R. C., Fischer, A. W., Singh, S., Aggarwal, G., Spina, S., Nana, A. L., Grinberg, L. T., Seeley, W. W., Surma, M. A., Klose, C., Paulo, J. A., Nguyen, A. D., Harper, J. W., Walther, T. C., Farese, R. V.
10.1101/2021.09.30.461806 — Posted: 2021-09-30
The activities of LRRK2 and GCase are positively correlated in clinical biospecimens and experimental models of Parkinson's disease
Kedariti, M., Frattini, E., Baden, P., Cogo, S., Civiero, L., Ziviani, E., Aureli, M., Kaganovich, A., Cookson, M. R., Stefanis, L. R., Surface, M., Deleidi, M., Di Fonzo, A., Alcalay, R. N., Rideout, H., Greggio, E., Plotegher, N.
10.1101/2021.09.27.461935 — Posted: 2021-09-28
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
Roosen, D. A., Landeck, N., Bonet-Ponce, L., Kluss, J., Conti, M., Smith, N., Saez-Atienzar, S., Ding, J., Beilina, A., Kumaran, R., Kaganovich, A., du Hoffmann, J., Williamson, C., Gershlick, D. C., Sampieri, L., Bleck, C. K. E., Liu, C., Bonifacino, J. S., Li, Y., Lewis, P. A., Cookson, M. R.
10.1101/830802 — Posted: 2021-09-16
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Waschbüsch, D., Berndsen, K., Lis, P., Knebel, A., Lam, Y. P., Alessi, D. R., Khan, A. R.
10.1101/2021.02.17.431620 — Posted: 2021-08-22

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