COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,388 Articles (22,816 medRxiv, 8,572 bioRxiv)

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Orthorhombic coronavirus main protease crystals provide a higher success rate in fragment screening
Barthel, T., Wollenhaupt, J., Benz, L. S., Reinke, P. Y. A., Zhang, L., Oelker, M., Lennartz, F., Taberman, H., Mueller, U., Meents, A., Hilgenfeld, R., Weiss, M. S.
10.1101/2025.08.20.671191 — Posted: 2025-08-20
Counterfactual evaluation of elementary and secondary school policies in the COVID-19 pandemic
Canfora, B., Escosio, R. A., Boldea, O., Nunes, A., Rozhnova, G.
10.1101/2025.08.17.25333861 — Posted: 2025-08-19
Effect of COVID-19 lockdown on sleep quality, sleep duration, and acute stress in Indian young adults
Soni, R., Gupta, I., Qureshi, S., Akhtar, N.
10.1101/2025.08.15.25333638 — Posted: 2025-08-19
Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization
Harit, A., Mor, M., Yefet, R., Izhaki-Tavor, L. S., Gal-Tanamy, M., Freund, N., Dessau, M.
10.1101/2025.08.17.670707 — Posted: 2025-08-19
Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants
Dadonaite, B., Harari, S., Larsen, B. B., Kampman, L., Harteloo, A., Elias-Warren, A., Chu, H. Y., Bloom, J. D.
10.1101/2025.08.18.671001 — Posted: 2025-08-19
Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice
Fan, C., Cohen, A. A., Dam, K.-M. A., Rorick, A. V., Priso Fils, A.-C. I., Yang, Z., Gnanapragasam, P. N., Segovia, L. N., Huey-Tubman, K. E., Moon, W. J., Lin, P. J., Bjorkman, P. J., Hoffmann, M. A.
10.1101/2025.08.18.670983 — Posted: 2025-08-19
SARS-CoV-2 S protein activates the HIV latent reservoir through the mTOR pathway
Xu, L., Shi, H., Chen, L., Wang, H., Shi, H., Miao, X., Li, S., Jiang, Y.
10.1101/2025.08.18.670887 — Posted: 2025-08-19
Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins
Kwissa, M., Mathayan, M., Salunkhe, S. S., Bakthavachalam, V., Ye, Z., Sanborn, M. A., Condo, S., Upadhye, A., Nemakal, A., Richner, J. M., Basu, S., Novak, R. M., Jacobson, J. R., Ganesh, B. B., Cerda, M., Utz, P. J., Krishnan, J. A., Prabhakar, B. S., Rehman, J.
10.1101/2025.08.18.670908 — Posted: 2025-08-19
CBM KG: A Comorbidity-Centric Knowledge Graph Uncovering Causal Pathomechanisms Between COVID-19 and Neurodegenerative Diseases
Atas Guvenilir, H., Sethumadhavan, P., Kaladharan, A., Vieira de Sa, R., Sridhar, A., Haferkamp, U., Pless, O., Marti-Sarrias, A., Acosta, S., Letoha, T., Hudak, A., Ohnmacht, J., Hefeng, F. Q., Hofmann-Apitius, M., Tom Kodamullil, A.
10.1101/2025.08.18.670790 — Posted: 2025-08-19
A Super-Resolution Spatial Atlas of SARS-CoV-2 Infection in Human Cells
Andronov, L., Han, M., Balaji, A., Zhu, Y., Qi, L. S., Moerner, W. E.
10.1101/2025.08.15.670620 — Posted: 2025-08-18

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).