COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,672 Articles (22,913 medRxiv, 8,759 bioRxiv)

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Identification of Novel Reproducible Combinatorial Genetic Risk Factors for Myalgic Encephalomyelitis in the DecodeME Patient Cohort and Commonalities with Long COVID
Sardell, J., Das, S., Pearson, M., Kolobkov, D., Malinowski, A., Fullwood, L., Sanna, M., Baxter, H., McLellan, K., Natt, M., Lamirel, D., Chowdhury, S., Rochlin, A., Strivens, M., Gardner, S.
10.64898/2025.12.01.25341362 — Posted: 2025-12-02
Development and structure-guided characterization of a novel ACE2-binding macrocyclic peptide
Benoit, R. M., Wang, J., Beyer, D., Abbas, A., Rodrigues, M. J., Wieser, M. M., Deupi, X., Müller, C., Suga, H., Bode, J. W.
10.64898/2025.12.01.690145 — Posted: 2025-12-02
IgG-Bridging-Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by A Low-Affinity Antibody
Lv, N., Chen, P., Dai, X., Xu, H., Li, Z., Shan, Z., Li, J., Guo, F., Chen, Y., Li, J., Huang, Y., Dong, G., Jiang, Y., Chen, L., Nan, X., Zhao, H., Zhang, K., Fan, S., Dong, Y., Liu, D., wang, x., Huang, D., Pan, X., Chen, C., Liu, Z., Yan, L.-T., Zhang, Q., Zhang, L., Zhao, Y., Yang, Y. R.
10.1101/2025.11.30.691454 — Posted: 2025-12-01
Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses
Munro, J., Melnyk, D., Schimanski, L., Afzal, M., Cohen, A. A., Keeffe, J., Bjorkman, P. J., James, W. S., Townsend, A. R., Tan, T. K.
10.1101/2025.11.28.691177 — Posted: 2025-12-01
SARS-CoV-2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways
Silva, B. E., dos Santos, R. S., Protasio, F., Cilli, E., Olivier, D., Belo, M. A., Charlie-Silva, I., Caixeta, E., Barchuk, A. R., Nunes-Silva, A., Romero, T., Galdino, G.
10.1101/2025.12.01.691535 — Posted: 2025-12-01
Investigating the Experiences of Frontline Health Workers in the Delivery of Healthcare during the COVID-19 Pandemic in Ghana.
Blankson, F. H., Andah, N. L., Brifo, H.
10.1101/2025.11.22.25338669 — Posted: 2025-11-30
Wastewater Genomic Surveillance Captures SARS-CoV-2 Early Detection, Cryptic Transmission, and Variant Dynamics
Veytsel, G., Sullivan, A., Lariscy, L., Lott, M., Lipp, E., Glenn, T., Carmola, L., Dishman, H., Bahl, J.
10.1101/2025.11.27.25332381 — Posted: 2025-11-30
Menstrual cycle phase and its association with COVID-19 vaccine side effects and subsequent infection: A study of period tracking app users.
Cooper, P. A., Boniface, E., Darney, B., Edelman, A., Sear, R., Shea, A., Vitzthum, V., Walters, S., Weber, K., Alvergne, A.
10.1101/2025.11.26.25341088 — Posted: 2025-11-30
Interaction and co-phase separation of SARS-CoV-2 nucleocapsid protein and human hnRNPA1 and its implications for viral life cycle
Gupta, P., Sahu, R., Nandi, I., Setty, S. R. G., Das, S., Singh, M.
10.1101/2025.11.28.691101 — Posted: 2025-11-28
Cross-Program Secondary Analyses and Public Health Innovation: The RADx Data Hub as a Resource for Integrated COVID-19 Research
Smith, K., Rose, P. W., Rivas, T., Mehri, N., Alonso Lozoya, O., Jeffers-Francis, L., King, M. D., Akdogan, M. U., Snipe, J., Farlow, B., Keller, M. A., Musen, M. A., Suber, S., Krishnamurthy, A.
10.1101/2025.11.26.25341110 — Posted: 2025-11-28

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).