COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,009 Articles (22,627 medRxiv, 8,382 bioRxiv)

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Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains
Gartner, M. J., Smith, M. J., Dapat, C., Liaw, Y. W., Tran, T., Suryadinata, R., Chen, J., Sun, G., Shepard, R. A., Taiaroa, G., Roche, M., Lee, W. S., Robinson, P., Polo, J. M., Subbarao, K., Neil, J. A.
10.1101/2025.04.13.648626 — Posted: 2025-04-15
Covering All Bases: A Computational Method to Design Broad-spectrum T-cell-inducing Vaccines Applied to Betacoronaviruses
Palmer, P., Fedosyuk, S., Parthasarathy, S., Holbrook, J., George, C., O'Reilly, L., Wiegand, L., Carnell, G. W., Heeney, J. L., Vishwanath, S.
10.1101/2025.04.14.648815 — Posted: 2025-04-15
Role of Dengue in SARS-CoV-2 Evolution in Dengue Endemic Regions
Mallick, A., Biswas, S.
10.1101/2025.04.13.648564 — Posted: 2025-04-15
Bat sarbecovirus WIV1-CoV bears an adaptive mutation that alters spike dynamics and enhances ACE2 binding
Tse, A. L., Lasso, G., McLellan, J. S., Chandran, K., Miller, E. H.
10.1101/2025.04.14.648681 — Posted: 2025-04-15
A Pan-Beta-Coronavirus Vaccine Bearing Conserved and Asymptomatic B- and T-Cell Epitopes Protect Against Highly Pathogenic Delta and Highly Transmissible Omicron SARS-CoV-2 Variants of Concern.
Vahed, H., Prakash, S., Quadiri, A., Ibraim, I. C., Omorogieva, E., Patel, S. J., Tadros, J. M., Liao, E. J., BENMOHAMED, L.
10.1101/2025.04.13.648648 — Posted: 2025-04-15
Neuroanatomy of catecholaminergic circuits in the brainstem and hypothalamus using T1-weighted and diffusion magnetic resonance imaging in humans: implications for brain-immune interactions, cardiovascular disease, neuropsychiatric disorders, stress response, and COVID-19
Hartung Toppa, P., Rushmore, R. J., Haggerty, K., Papadimitriou, G., Yeterian, E., Castaneyra-Perdomo, A. L., Makris, N.
10.1101/2025.04.11.644973 — Posted: 2025-04-14
REAL-WORLD IMPACT OF THE FIRST WAVE OF THE COVID-19 PANDEMIC ON THE CYSTIC FIBROSIS COMMUNITY THROUGHOUT EUROPE
Bardin, E. E., Lammertyn, E., De Keyser, H.
10.1101/2025.04.11.25325660 — Posted: 2025-04-14
Systematic differences were identified for symptoms of Omicron infected individuals between early and late stage of the COVID-19 pandemic in China
Yang, C., Zhang, Y., Yang, Y., Mi, B., Shen, M., Nian, Y., Wang, J., Cao, S., Liu, J., Abolfazli, P., Huang, H., Wei, Z., Liu, L., Wu, Q., Zhang, T., Zhang, S.
10.1101/2025.04.10.25325424 — Posted: 2025-04-14
Customizable host and viral transcript enrichment using CRISPR-Cas9 long-read sequencing for isoform discovery and validation
Nguyen, A. N. T., Zhang, J., Zhang, S., Pitt, M. E., Ganesamoorthy, D., Fritzlar, S., Chang, J. J. Y., Londrigan, S., Coin, L. J. M.
10.1101/2025.04.11.648353 — Posted: 2025-04-14
Mucin anchoring of SARS-CoV-2 neutralizing nanobinders increases intranasal antiviral efficacy
Rocha Gomes, J., Jacquelin, J., Donchet, A., Lejal, N., Nevers, Q., Konjkowski, B., Le Poder, S., Delmas, B., MEUNIER, N.
10.1101/2025.04.10.648177 — Posted: 2025-04-14

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).