COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,668 Articles (22,913 medRxiv, 8,755 bioRxiv)

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Persistent CD4+ T cell functional deficits during recovery from prolonged symptomatic SARS-CoV-2 infection
Ziegler, J., Lawrence, C., Turner, S., Pezant, N., Redinger, N., Guthridge, C., Smith, K., Chen, J., Guthridge, J. M., James, J. A., Rankin, S. M., Thompson, L. F., Farris, A. D., Kovats, S.
10.64898/2025.12.03.692161 — Posted: 2025-12-04
The impact of COVID-19 on gastrointestinal diseases in vaccinated and unvaccinated individuals: a population-based cohort study in England
Al Arab, M., Cezard, G., Crooks, C. J., Wei, Y., Horne, E., Palmer, T. M., Coronado, J. I. C., Green, M., Fisher, L., Walker, A. J., Massey, J., Davy, S., Mehrkar, A., Bacon, S., Wood, A., Goldacre, B., Chaturvedi, N., Sterne, J. A. C., Walker, V., Denholm, R.
10.64898/2025.12.01.25341357 — Posted: 2025-12-02
Risk Factors for Severe Post-COVID Condition in Children, Adolescents, and Young Adults
Donath, Q., Haegele, M., Schindler, D., Welzhofer, T., Christa, C., Grabbe, A., Leone, A., Ilhan, C., Weidmann, C., Eberhartinger, M., Bechtold, S., Bursch, N., Wolf, H., Hieber, H., Peo, L.-C., Bucka, L. A., Stojanov, S., Warlitz, C., Alberer, M., Gerrer, K., Hausruckinger, A., Mittelstrass, K., Wendtner, C.-M., Hoechstetter, M. A., Gruebl, A., Toepfner, N., Pricoco, R., Scheibenbogen, C., Mihatsch, L. L., Behrends, U.
10.64898/2025.12.01.25341171 — Posted: 2025-12-02
How COVID-19 vaccination in England varied by geography, demography, deprivation and registry: Bayesian ecological modelling
Dropkin, G.
10.64898/2025.12.01.25341337 — Posted: 2025-12-02
Modeling the Cost-Effectiveness of the Next-Generation COVID-19 mRNA-1283 Vaccine in the United States
Fust, K., Kohli, M., Joshi, K., Cartier, S., Lee, A., Van de Velde, N., Weinstein, M., Beck, E.
10.64898/2025.12.01.25341380 — Posted: 2025-12-02
Mental health trajectories of children and adolescents up to five years after the onset of the COVID-19 pandemic: a longitudinal study
Richard, V., Lorthe, E., Dumont, R., Bovio, N., Fernandez, N., Nehme, M., Barbe, R. P., Posfay-Barbe, K. M., Guessous, I., Stringhini, S.
10.64898/2025.11.30.25340982 — Posted: 2025-12-02
Identification of Novel Reproducible Combinatorial Genetic Risk Factors for Myalgic Encephalomyelitis in the DecodeME Patient Cohort and Commonalities with Long COVID
Sardell, J., Das, S., Pearson, M., Kolobkov, D., Malinowski, A., Fullwood, L., Sanna, M., Baxter, H., McLellan, K., Natt, M., Lamirel, D., Chowdhury, S., Rochlin, A., Strivens, M., Gardner, S.
10.64898/2025.12.01.25341362 — Posted: 2025-12-02
Development and structure-guided characterization of a novel ACE2-binding macrocyclic peptide
Benoit, R. M., Wang, J., Beyer, D., Abbas, A., Rodrigues, M. J., Wieser, M. M., Deupi, X., Müller, C., Suga, H., Bode, J. W.
10.64898/2025.12.01.690145 — Posted: 2025-12-02
IgG-Bridging-Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by A Low-Affinity Antibody
Lv, N., Chen, P., Dai, X., Xu, H., Li, Z., Shan, Z., Li, J., Guo, F., Chen, Y., Li, J., Huang, Y., Dong, G., Jiang, Y., Chen, L., Nan, X., Zhao, H., Zhang, K., Fan, S., Dong, Y., Liu, D., wang, x., Huang, D., Pan, X., Chen, C., Liu, Z., Yan, L.-T., Zhang, Q., Zhang, L., Zhao, Y., Yang, Y. R.
10.1101/2025.11.30.691454 — Posted: 2025-12-01
Development of a Recombinant Single-Cycle Influenza Viral Vector as an Intranasal Vaccine against SARS-CoV-2 and SARS-like Betacoronaviruses
Munro, J., Melnyk, D., Schimanski, L., Afzal, M., Cohen, A. A., Keeffe, J., Bjorkman, P. J., James, W. S., Townsend, A. R., Tan, T. K.
10.1101/2025.11.28.691177 — Posted: 2025-12-01

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).