Channel:  HHMI

1037 Articles

Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Eggers, A. R., Chen, K., Soczek, K. M., Tuck, O. T., Doherty, E. E., Thornton, B. W., Xu, B., Trinidad, M. I., Doudna, J. A.
10.1101/2023.12.14.571777 — Posted: 2023-12-15
Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
Martin, A., Lopez-Alfonzo, E. M., Saurabh, A., Zarafshan, S., Presse, S.
10.1101/2023.12.14.571752 — Posted: 2023-12-15
A translation-independent directed evolution strategy to engineer aminoacyl-tRNA synthetases
Soni, C., Prywes, N., Hall, M., Savage, D. F., Schepartz, A., Chatterjee, A.
10.1101/2023.12.13.571473 — Posted: 2023-12-14
The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation
Mehta, N., Mondal, S., Watson, E. T., Cui, Q., Chapman, E. R.
10.1101/2023.08.11.551903 — Posted: 2023-12-13
Rapid, concerted switching of the neural code in inferotemporal cortex
Shi, Y., Bi, D., Hesse, J. K., Lanfranchi, F. F., Chen, S., Tsao, D. Y.
10.1101/2023.12.06.570341 — Posted: 2023-12-13
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin
Welsh, F. C., Eguia, R. T., Lee, J. M., Haddox, H. K., Galloway, J., Vinh, N. V., Loes, A. N., Huddleston, J., Yu, T. C., Le, M. Q., Nhat, N. T., Thanh, N. T. L., Greninger, A. L., Chu, H. Y., Englund, J. A., Bedford, T., Matsen, F. A., Boni, M. F., Bloom, J. D.
10.1101/2023.12.12.571235 — Posted: 2023-12-12
Single molecule studies of the native hair cell mechanosensory transduction complex
Clark, S., Mitra, J., Elferich, J., Goehring, A., Ge, J., Ha, T., Gouaux, E.
10.1101/2023.12.11.571162 — Posted: 2023-12-12
RluA is the major mRNA pseudouridine synthase in Escherichia coli
Schaening Burgos, C., Li, G.-W., Gilbert, W. V.
10.1101/2023.12.08.570740 — Posted: 2023-12-12
Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis
Constable, S., Ott, C. M., Lemire, A. L., White, K., Lim, A., Lippincott-Schwartz, J., Mukhopadhyay, S.
10.1101/2023.12.07.565993 — Posted: 2023-12-11
Rapid long-distance migration of RPA on single stranded DNA occurs through intersegmental transfer utilizing multivalent interactions
Pangeni, S., Biswas, G., Kaushik, V., Kuppa, S., Yang, O., Lin, C.-T., Mishra, G., Levy, Y., Antony, E., Ha, T.
10.1101/2023.12.09.570606 — Posted: 2023-12-10

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