Channel:  HHMI

1037 Articles

Unselfish meiotic drive maintains heterozygosity in a parthenogenetic ant
Lacy, K. D., Hart, T., Kronauer, D. J. C.
10.1101/2024.02.09.579553 — Posted: 2024-02-12
Multiplex generation and single cell analysis of structural variants in a mammalian genome
Pinglay, S., Lalanne, J.-B., Daza, R. M., Koeppel, J., Li, X., Lee, D. S., Shendure, J.
10.1101/2024.01.22.576756 — Posted: 2024-02-12
Induction and in silico staging of human gastruloids with neural tube, segmented somites & advanced cell types
Hamazaki, N., Yang, W., Kubo, C., Qiu, C., Martin, B. K., Garge, R. K., Regalado, S. G., Nichols, E., Lee, C., Daza, R. M., Srivatsan, S., Shendure, J.
10.1101/2024.02.10.579769 — Posted: 2024-02-12
The Cas10 nuclease activity relieves host dormancy to facilitate spacer acquisition and retention during type III-A CRISPR immunity
Aviram, N., Shilton, A., Lyn, N., Reis, B. S., Brivanlou, A., Marraffini, L. A.
10.1101/2024.02.11.579731 — Posted: 2024-02-12
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications
Cookis, T., Lydecker, A., Sauer, P. V., Kasinath, V., Nogales, E.
10.1101/2024.02.09.579730 — Posted: 2024-02-10
Interplay of condensation and chromatin binding underlies BRD4 targeting
Strom, A. R., Eeftens, J. M., Polyachenko, Y., Weaver, C. J., Watanabe, H.-F., Bracha, D., Orlovsky, N. D., Jumper, C. C., Jacobs, W. M., Brangwynne, C. P.
10.1101/2024.02.07.579384 — Posted: 2024-02-07
Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
Carr, C. R., Crawford, K. H., Murphy, M., Galloway, J. G., Haddox, H. K., Matsen, F. A., Andersen, K. G., King, N. P., Bloom, J. D.
10.1101/2024.02.05.579020 — Posted: 2024-02-06
A Functional and Non-Homuncular Representation of the Larynx in the Primary Motor Cortex of Mice, a Vocal Non-Learner
Vargas, C. D. M., Agravat, R. K., Waidmann, E. N., Bochalis, C., Bermudez, H., Giannakopoulos, T., Jarvis, E. D.
10.1101/2024.02.05.579004 — Posted: 2024-02-06
Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning
Laubscher, E., Wang, X., Razin, N., Dougherty, T., Xu, R., Ombelets, L., Pao, E., Moffitt, J., Yue, Y., Van Valen, D. A.
10.1101/2023.09.03.556122 — Posted: 2024-02-05
Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.
Visker, J. R., Cluntun, A. A., Velasco-Silva, J. N., Eberhardt, D. R., Shankar, T. S., Hamouche, R., Ling, J., Kwak, H., Hillas, Y., Aist, I., Tseliou, E., Navankasattusas, S., Chaudhuri, D., Ducker, G. S., Drakos, S. G., Rutter, J.
10.1101/2024.02.01.577463 — Posted: 2024-02-04

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