Channel:  HHMI

1037 Articles

Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis
Johnson, K., Seidel, J. M., Cech, T. R.
10.1101/2024.04.01.587626 — Posted: 2024-04-02
The LuxO-OpaR quorum-sensing cascade differentially controls Vibriophage VP882 lysis-lysogeny decision making in liquid and on surfaces
Santoriello, F., Bassler, B. L.
10.1101/2024.04.02.587679 — Posted: 2024-04-02
Broadly neutralizing antibodies against emerging delta-coronaviruses
Rexhepaj, M., Park, Y.-J., Perruzza, L., Asarnow, D., McCallum, M., Culap, K., Saliba, C., Leoni, G., Balmeli, A., Yoshiyama, C., Dickinson, M. S., Quispe, J., Brown, J. T., Tortorici, M. A., Sprouse, K. R., Taylor, A. L., Starr, T. N., Corti, D., Begnini, F., Veesler, D.
10.1101/2024.03.27.586411 — Posted: 2024-04-01
Directed Evolution of Acoustic Reporter Genes Using High-Throughput Acoustic Screening
Hurt, R. C., Jin, Z., Soufi, M., Wong, K. K., Sawyer, D. P., Shen, H. K., Dutka, P., Deshpande, R., Zhang, R., Mittelstein, D. R., Shapiro, M. G.
10.1101/2024.03.30.587094 — Posted: 2024-04-01
Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers
Tang, J., Weiser, N. E., Wang, G., Chowdhry, S., Curtis, E. J., Zhao, Y., Wong, I. T.-L., Marinov, G. K., Li, R., Hanoian, P., Tse, E., Hansen, R., Plum, J., Steffy, A., Milutinovic, S., Meyer, S. T., Altemose, N., Curtis, C., Greenleaf, W. J., Bafna, V., Benkovic, S. J., Pinkerton, A. B., Kasibhatla, S., Hassig, C. A., Mischel, P. S., Chang, H. Y.
10.1101/2024.03.29.586681 — Posted: 2024-03-29
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism
Hou, K., Ge, P., Sawaya, M. R., Dolinsky, J. L., Yang, Y., Jiang, Y. X., Lutter, L., Boyer, D. R., Cheng, X., Pi, J., Zhang, J., Lu, J., Yang, S., Yu, Z., Feigon, J., Eisenberg, D. S.
10.1101/2024.03.25.586668 — Posted: 2024-03-29
NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, A., Eyunni, S., Verma, B. K., Young, E., Liu, L., George, J., Aras, S., Das, C. K., Mannan, R., ur Rasool, R., Luo, J., Carson, S. E., Mitchell-Velasquez, E., Liu, Y., Xiao, L., Gajjala, P. R., Jaber, M., Wang, X., He, T., Qiao, Y., Pang, M., Zhang, Y., Alhusayan, M., Cao, X., Tavana, O., Hou, C., Wang, Z., Ding, K., Chinnaiyan, A. M., Asangani, I. A.
10.1101/2024.02.22.581560 — Posted: 2024-03-29
The Molecular Architecture of the Nuclear Basket
Singh, D., Soni, N., Hutchings, J., Echeverria, I., Shaikh, F., Duquette, M., Suslov, S., Li, Z., van Eeuwen, T., Molloy, K., Shi, Y., Wang, J., Guo, Q., Chait, B. T., Fernandez-Martinez, J., Rout, M. P., Sali, A., Villa, E.
10.1101/2024.03.27.587068 — Posted: 2024-03-28
Global coral genomic vulnerability explains recent reef losses
Selmoni, O., Cleves, P. A., Exposito-Alonso, M.
10.1101/2024.03.25.586253 — Posted: 2024-03-25
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan
Jayne, L., Lavin-Peter, A., Roessler, J., Tyshkovskiy, A., Antoszewski, M., Ren, E., Markovski, A., Sun, S., Yao, H., Sankaran, V. G., Gladyshev, V. N., Brooke, R. T., Horvath, S., Griffith, E. C., Hrvatin, S.
10.1101/2024.03.20.585828 — Posted: 2024-03-25

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