Channel:  HHMI

1037 Articles

Condensate-driven interfacial forces reposition DNA loci and measure chromatin viscoelasticity
Strom, A. R., Kim, Y., Zhao, H., Orlovsky, N. D., Chang, Y.-C., Kosmirlj, A., Storm, C., brangwynne, C. P.
10.1101/2023.02.27.530281 — Posted: 2023-03-01
Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy
Niemi, N. M., Serrano, L. R., Muehlbauer, L. K., Balnis, C., Kozul, K.-L., Rashan, E. H., Shishkova, E., Schueler, K. L., Keller, M. P., Attie, A. D., Pagan, J., Coon, J. J., Pagliarini, D. J.
10.1101/2023.02.28.530351 — Posted: 2023-03-01
Requirements for establishment and epigenetic stability of mammalian heterochromatin
Tatarakis, A., Saini, H., Moazed, D.
10.1101/2023.02.27.530221 — Posted: 2023-02-28
Three rules for epigenetic inheritance of human Polycomb silencing
Shafiq, T., Moazed, D.
10.1101/2023.02.27.530239 — Posted: 2023-02-28
Rapid resistance profiling of SARS-CoV-2 protease inhibitors
Moghadasi, S. A., Biswas, R., Harki, D. A., Harris, R.
10.1101/2023.02.25.530000 — Posted: 2023-02-27
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
Durfee, C., Temiz, N. A., Levin-Klein, R., Argyris, P., Alsoe, L., Carracedo, S., Alonso, A., Proehl, J., Holzhauer, A., Seeman, Z., Lin, Y.-H. T., Vogel, R. I., Sotillo, R., Nilsen, H., Harris, R.
10.1101/2023.02.24.529970 — Posted: 2023-02-25
O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations
Huynh, D. T., Hu, J., Schneider, J. R., Tsolova, K. N., Soderblom, E. J., Watson, A. J., Chi, J.-T. A., Evans, C. S., Boyce, M.
10.1101/2023.02.22.529563 — Posted: 2023-02-22
Marginal specificity in protein interactions constrains evolution
Ghose, D. A., Przydzial, K. E., Mahoney, E. M., Keating, A. E., Laub, M. T.
10.1101/2023.02.18.529082 — Posted: 2023-02-19
Regulated assembly and neurosteroid modulation constrain GABAA receptor pharmacology in vivo
Sun, C., Zhu, H., Clark, S. A., Gouaux, E.
10.1101/2023.02.16.528867 — Posted: 2023-02-16
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
Li, Y.-D., Ma, M. W., Hassan, M. M., Hunkeler, M., Teng, M., Puvar, K., Lumpkin, R., Sandoval, B., Jin, C. Y., Ficarro, S. B., Wang, M. Y., Xu, S., Groendyke, B. J., Sigua, L. H., Tavares, I., Zou, C., Tsai, J. M., Park, P. M. C., Yoon, H., Majewski, F. C., Marto, J. A., Qi, J., Nowak, R. P., Donovan, K. A., Slabicki, M., Gray, N. S., Fischer, E. S., Ebert, B. L.
10.1101/2023.02.14.528208 — Posted: 2023-02-15

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