Channel: Babraham Institute

183 Articles

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Genome-scale oscillations in DNA methylation during exit from pluripotency

Rulands, S., Lee, H. J., Clark, S. J., Angermueller, C., Smallwood, S. A., Krueger, F., Mohammed, H., Dean, W., Nichols, J., Rugg-Gunn, P., Kelsey, G., Stegle, O., Simons, B. D., Reik, W.

10.1101/338822 — Posted: 2018-06-05

PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

Stark, A.-K., Chandra, A., Chakraborty, K., Alam, R., Carbonaro, V., Clark, J., Sriskantharajah, S., Bradley, G., Richter, A. G., Banham-Hall, E., Clatworthy, M. R., Nejentsev, S., Hamblin, J. N., Hessel, E. M., Condliffe, A. M., Okkenhaug, K.

10.1101/280651 — Posted: 2018-03-18

Nucleosome remodelling at origins of Global Genome-Nucleotide Excision Repair occurs at the boundaries of higher-order chromatin structure

van Eijk, P., Nandi, S. P., Yu, S., Bennett, M., Leadbitter, M., Teng, Y., Reed, S.

10.1101/283747 — Posted: 2018-03-16

Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

Olova, N. N., Krueger, F., Andrews, S., Oxley, D., Berrens, R. V., Branco, M. R., Reik, W.

10.1101/165449 — Posted: 2018-03-02

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

Clark, S. J., Argelaguet, R., Kapourani, C.-A., Stubbs, T. M., Lee, H. J., Alda-Catalinas, C., Krueger, F., Sanguinetti, G., Kelsey, G., Marioni, J. C., Stegle, O., Reik, W.

10.1101/138685 — Posted: 2018-01-17

Tri-methylation of Histone H3 Lysine 4 Facilitates Gene Expression in Ageing Cells

Cruz, C., Della Rosa, M., Krueger, C., Gao, Q., Field, L., Houseley, J.

10.1101/238048 — Posted: 2017-12-22

Spatial RNA proximities reveal a bipartite nuclear transcriptome and territories of differential density and transcription elongation rates

Morf, J., Wingett, S. W., Farabella, I., Cairns, J., Furlan-Magaril, M., Liu, X., Craig, F. F., Andrews, S., Marti-Renom, M. A., Fraser, P.

10.1101/196147 — Posted: 2017-09-29

A non-catalytic role of TET3 promotes open chromatin and enhances global transcription

Krueger, C., Peat, J. R., Eckersley-Maslin, M. A., Hore, T. A., Mohammed, H., Andrews, S. R., Dean, W., Reik, W.

10.1101/177626 — Posted: 2017-08-17

Multi-Tissue DNA Methylation Age Predictor In Mouse

Stubbs, T. M., Bonder, M. J., Stark, A.-K., Krueger, F., BI Ageing Clock Team, , von Meyenn, F., Stegle, O., Reik, W.