Channel:  Francis Crick Institute

1,177 Articles

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MRTF-dependent cytoskeletal dynamics drive efficient cell cycle progression
Nielsen, J. C., Benito-Jardon, M., Petrela, N. C., Diring, J., Bellamy, S., Treisman, R.
10.1101/2025.06.06.657372 — Posted: 2025-06-07
Multimodal profiling unveils a reversible basal-like breast cancer cell state resistant to AKT inhibition
Ratcliffe, C. D. H., Sparks, H., Boezio, G. L. M., Alexandrov, Y., Jenkins, R. P., Le Marois, A., Soro-Barrio, P., Lee, R., Strohbuecker, S., Joshi, S., Ellis, J. K., Fortier, A.-M., Gustafsson, N., Cunha, A. C., Park, M., MacRae, J. I., Serio, A., Briscoe, J., Riddell, A., Barry, S. T., Dunsby, C., Sahai, E.
10.1101/2025.06.06.658331 — Posted: 2025-06-07
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics
Autorino, C., Khoromskaia, D., Harari, L., Floris, E., Booth, H., Pallares-Cartes, C., Petrasiunaite, V., Dorrity, M., Corominas-Murtra, B., Hadjivasiliou, Z., Petridou, N.
10.1101/2025.06.06.658228 — Posted: 2025-06-06
C9orf72 polyGA knock-in mice exhibit mild motor and proteomic changes consistent with ALS/FTD
Milioto, C., Carcole, M., Zanovello, M., Ahmed, M., Nirujogi, R. S., Biggs, D., Katona, E., Glaria, I., Santos, A., Devoy, A., Fratta, P., Alessi, D. R., Davies, B., Greensmith, L., Fisher, E., Isaacs, A. M.
10.1101/2025.05.30.656994 — Posted: 2025-06-02
Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
Goldsworthy, S., Fertan, E., Dyal, P., Domoney, S., Livesey, F., Klenerman, D., Patani, R., Hung, C.
10.1101/2025.05.27.656416 — Posted: 2025-06-01
Beneficial and detrimental consequences of AHR activation in intestinal infection
Diaz, O. P., zhou, L., Barrington, C., Lindquist, D., Graelmann, F., Wincent, E., Stockinger, B.
10.1101/2025.05.28.656570 — Posted: 2025-06-01
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Roeselova, A., Shivakumaraswamy, S., Jurkeviciute, G., He, J.-Z., Auburger, J., Schmitt, J., Kramer, G., Bukau, B., Enchev, R. I., Balchin, D.
10.1101/2025.05.27.656346 — Posted: 2025-05-30
The penetrant chordoid glioma PRKCA mutation is an oncogenic gain-of-function kinase inactivation eliciting early onset chondrosarcoma in mice.
Calleja, v., Henry, J. C., Cobbaut, M., Sewell, J., Rizzoti, K., Houghton, F., Boeing, S., Anyanwu, N., Varsani-Brown, S., Snoeks, T., Suarez-Bonnet, A., Priestnall, S. L., McDonald, N. Q., Cameron, A. J., Parker, P. J.
10.1101/2025.05.28.656646 — Posted: 2025-05-29
Gene network architecture, mutation and selection collectively drive developmental pattern evolvability and predictability
Booth, H., Hadjivasiliou, Z.
10.1101/2024.12.23.630099 — Posted: 2025-05-29
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Fontaine, M., Vives, M. J. D., Saez, M., Maizels, R., Finnie, E., Briscoe, J., Rand, D. A.
10.1101/2025.05.28.656648 — Posted: 2025-05-28

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