Channel:  The Howard Hughes Medical Institute (HHMI)

2,322 Articles

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The big tau splice isoform resists Alzheimer's-related pathological changes
Chung, D.-e. C., Deng, X., Yalamanchili, H. K., Revelli, J.-P., Han, A. L., Tadros, B., Richman, R., Dias, M., Alavi Naini, F., Boeynaems, S., Hyman, B. T., Zoghbi, H. Y.
10.1101/2024.07.30.605685 — Posted: 2024-07-31
Amortized template-matching of molecular conformations from cryo-electron microscopy images using simulation-based inference
Dingeldein, L., Silva-Sanchez, D., Evans, L., D'Imprima, E., Grigorieff, N., Covino, R., Cossio, P.
10.1101/2024.07.23.604154 — Posted: 2024-07-31
CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation
Soczek, K. M., Cofsky, J. C., Tuck, O. T., Shi, H., Doudna, J. A.
10.1101/2024.07.31.606079 — Posted: 2024-07-31
Diversity in Notch ligand-receptor signaling interactions
Kuintzle, R., Santat, L. A., Elowitz, M. B.
10.1101/2023.08.24.554677 — Posted: 2024-07-31
Chemical genetics reveals cross-activation of plant developmental signaling by the immune peptide-receptor pathway
Herrmann, A., Sepuru, K. M., Endo, H., Nakagawa, A., Kusao, S., Bai, P., Ziadi, A., Kato, H., Sato, A., Liu, J., Shan, L., Kimura, S., Itami, K., Uchida, N., Hagihara, S., Torii, K. U.
10.1101/2024.07.29.605519 — Posted: 2024-07-30
Gustatory Thalamic Neurons Mediate Aversive Behaviors
Cao, F., Park, S., Pauli, J. L., Seo, E. Y., Palmiter, R. D.
10.1101/2024.07.29.605702 — Posted: 2024-07-30
Paternal genome elimination creates contrasting evolutionary trajectories in male and female citrus mealybugs
Mongue, A. J., Woodman, T., Marshall, H., Garber, A. J., Franco, J. C., McCutcheon, J. P., Ross, L.
10.1101/2024.07.28.604693 — Posted: 2024-07-30
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1
Harold, R. L., Tulsian, N. K., Narasimamurthy, R., Yaitanes, N., Hernandez, M. G. A., Lee, H.-W., Crosby, P., Tripathi, S., Virshup, D. M., Partch, C. L.
10.1101/2023.04.24.538174 — Posted: 2024-07-29
A bacterial TIR-based immune system senses viral capsids to initiate defense
Roberts, C., Fishman, C., Banh, D., Marraffini, L. A.
10.1101/2024.07.29.605636 — Posted: 2024-07-29
ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
Rincon-Torroella, J., Dal Molin, M., Mog, B., Han, G., Watson, E., Wyhs, N., Ishiyama, S., Ahmedna, T., Minn, I., Azad, N. S., Bettegowda, C., Papadopoulos, N., Kinzler, K. W., Zhou, S., Vogelstein, B., Gabrielson, K. L., Sur, S.
10.1101/2023.07.23.550207 — Posted: 2024-07-29

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