Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing
Shi, H., Al-Sayyad, N., Wasko, K., Trinidad, M. I., Doherty, E. E., Vohra, K., Boger, R. S., Colognori, D., Cofsky, J. C., Skopintsev, P., Bryant, Z., Doudna, J. A.
10.1101/2024.10.01.616117 — Posted: 2024-10-02
Remote activation of place codes by gaze in a highly visual animal
Payne, H. L., Aronov, D.
10.1101/2024.09.30.615982 — Posted: 2024-10-02
An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer
Magesh, R. Y., Kaur, A. N., Keller, F. N., Frederick, A., Tseyang, T., Haley, J. A., Rivera Nieves, A. M., Liang, A. C., Guertin, D., Spinelli, J., Elledge, S. J., Watson, E. V.
10.1101/2024.09.30.615609 — Posted: 2024-10-01
Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells
Grzywa, T., Mehta, N., Cossette, B., Romanov, A., Paruzzo, L., Ramasubramanian, R., Cozzone, A., Morgan, D., Sukaj, I., Bergaggio, E., Tannir, R., Kadauke, S., Myers, R., Yousefpour, P., Ghilardi, G., Schuster, S., Neeser, A., Frey, N., Goncalves, B., Zhang, L., Abraham, W., Suh, H., Ruella, M., Grupp, S., Chiarle, R., Wittrup, K. D., Ma, L., Irvine, D. J.
10.1101/2024.04.16.589780 — Posted: 2024-10-01
Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording
McDiarmid, T. A., Taylor, M. L., Chen, W., Chardon, F. M., Choi, J., Liao, H., Li, X., Kim, H., Lalanne, J.-B., Li, T., Nathans, J. F., Martin, B. K., Knuth, J., Coradini, A. L. V., Gray, J. M., Pinglay, S., Shendure, J.
10.1101/2024.09.30.615957 — Posted: 2024-10-01
Latent-TGF-β has a domain swapped architecture
Jin, M., Seed, R., Shing, T., Cheng, Y., Nishimura, S.
10.1101/2024.09.27.615443 — Posted: 2024-09-30
Mapping and engineering RNA-controlled architecture of the multiphase nucleolus
Quinodoz, S. A., Jiang, L., Abu-Alfa, A. A., Comi, T. J., Zhao, H., Yu, Q., Wiesner, L. W., Botello, J. F., Donlic, A., Soehalim, E., Zorbas, C., Wacheul, L., Kosmrlj, A., Lafontaine, D. L., Klinge, S., Brangwynne, C. P.
10.1101/2024.09.28.615444 — Posted: 2024-09-29
Functional protein mining with conformal guarantees
Boger, R. S., Chithrananda, S., Angelopoulos, A. N., Yoon, P. H., Jordan, M. I., Doudna, J. A.
10.1101/2024.06.27.601042 — Posted: 2024-09-28
DNA polymerase Zeta is a robust reverse transcriptase
Mayle, R., Holloman, W. K., O'Donnell, M. E.
10.1101/2024.09.27.615452 — Posted: 2024-09-28
Dysregulation of the fluid homeostasis system by aging
Jang, H., Behne Sharma, A., Dan, U., Wong, J. H., Knight, Z. A., Garrison, J. L.
10.1101/2024.09.26.615271 — Posted: 2024-09-27

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