Channel:  The Howard Hughes Medical Institute (HHMI)

2,124 Articles

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KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes
Xie, X., Zhang, O., Yeo, M. J., Lee, C., Harry, S. A., Paul, L., Li, Y., Payne, N. C., Nam, E., Kwok, H. S., Jiang, H., Mao, H., Hadley, J. L., Lin, H., Batts, M., Gosavi, P. M., D'Angiolella, V., Cole, P. A., Mazitschek, R., Northcott, P. A., Zheng, N., Liau, B. B.
10.1101/2024.05.14.593970 — Posted: 2024-05-14
Ultrasound-actuated drug delivery with acoustic percolation switches
Abundo, M. P., Tifrea, A. T., Buss, M. T., Barturen-Larrea, P., Jin, Z., Malounda, D., Shapiro, M. G.
10.1101/2024.05.10.593654 — Posted: 2024-05-14
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
Geraghty, A. C., Acosta-Alvarez, L., Rotiroti, M. C., Dutton, S., O'Dea, M., Woo, P., Xu, H., Shamardani, K., Mancusi, R., Ni, L., Mulinyawe, S. B., Kim, W. J., Liddelow, S., Majzner, R. G., Monje, M.
10.1101/2024.05.14.594163 — Posted: 2024-05-14
Complex structural variation and behavioral interactions underpin a balanced sexual mimicry polymorphism
Dodge, T. O., Kim, B. Y., Baczenas, J. J., Banerjee, S. M., Gunn, T. R., Donny, A. E., Given, L. A., Rice, A. R., Haase Cox, S. K., Weinstein, M. L., Cross, R., Moran, B. M., Haber, K., Haghani, N. B., Machin Kairuz, J. A., Gellert, H. R., Du, K., Aguillon, S. M., Tudor, M. S., Gutierrez-Rodriguez, C., Rios-Cardenas, O., Morris, M. R., Schartl, M., Powell, D. L., Schumer, M.
10.1101/2024.05.13.594052 — Posted: 2024-05-14
Structure of the lens MP20 mediated adhesive junction
Nicolas, W. J., Shiriaeva, A., Martynowycz, M. W., Grey, A. C., Ruma, Y., Donaldson, P. J., Gonen, T.
10.1101/2024.05.13.594022 — Posted: 2024-05-14
Asymmetric Engagement of Dimeric CRL3KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes
Yeo, M. J., Zhang, O., Xie, X., Nam, E., Payne, N. C., Gosavi, P. M., Kwok, H. S., Iram, I., Lee, C., Li, J., Chen, N. J., Jiang, H., Wang, Z. A., Lee, K., Mao, H., Harry, S. A., Barakat, I. A., Takahashi, M., Waterbury, A. L., Barone, M., Mattevi, A., Bar-Peled, L., Cole, P. A., Mazitschek, R., Liau, B. B., Zheng, N.
10.1101/2024.05.14.593897 — Posted: 2024-05-14
Proteasomal control of anti-CRISPRs for the regulation of CRISPR/Cas9 activity using Cas9-ACROBAT
Martin, T. D., Watson, E. V., Choi, M. Y., Nabet, B., Gray, N. S., Xu, Q., Elledge, S.
10.1101/2024.05.13.593596 — Posted: 2024-05-13
Coumarin as a general switching auxiliary to prepare photochromic and spontaneously blinking fluorophores
Jradi, F., English, B. P., Brown, T. A., Arron, J., Khuon, S., Galbraith, J. A., Galbraith, C. G., Lavis, L. D.
10.1101/2024.05.12.593749 — Posted: 2024-05-12
The Janelia Atalanta plasmids provide a simple and efficient CRISPR/Cas9-mediated homology directed repair platform for Drosophila
Stern, D. L., Kim, E., Berhman, E. L.
10.1101/2023.06.17.545412 — Posted: 2024-05-11
Imaging the extracellular matrix in live tissues and organisms with a glycan-binding fluorophore
Fiore, A., Yu, G., Northey, J. J., Patel, R., Ravenscroft, T. A., Ikegami, R., Kolkman, W., Kumar, P., Grimm, J. B., Dilan, T. L., Ruetten, V. M. S., Ahrens, M. B., Shroff, H., Lavis, L. D., Wang, S., Weaver, V. M., Pedram, K.
10.1101/2024.05.09.593460 — Posted: 2024-05-10

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