Channel:  The Howard Hughes Medical Institute (HHMI)

2,303 Articles

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Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA
Chen, L., Maes, M., Cochran, A. M., Avila, J. R., Derbyshire, P., Sklenar, J., Haas, K. M., Villen, J., Menke, F., Torii, K. U.
10.1101/2024.09.20.612365 — Posted: 2024-09-21
Modulating DNA Polα Enhances Cell Reprogramming Across Species
Ranjan, R., Ma, B., Gleason, R. J., Liao, Y., Bi, Y., Davis, B. E. M., Yang, G., Clark, M., Mahajan, V., Condon, M., Broderick, N. A., Chen, X.
10.1101/2024.09.19.613993 — Posted: 2024-09-20
High-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases
Haynes, L. M., Holding, M. L., DiGiovanni, H., Siemieniak, D., Ginsburg, D.
10.1101/2024.09.16.612699 — Posted: 2024-09-20
MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function
Lin, J., Unge, J., Gonen, T.
10.1101/2024.09.18.613782 — Posted: 2024-09-19
Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans
Ludin, A., Stirtz, G. L., Tal, A., Nirmal, A. J., Besson, N., Jones, S. M., Pfaff, K. L., Manos, M., Liu, S., Barrera, I., Gong, Q., Rodrigues, C. P., Sahu, A., Jerison, E., Alessi, J. V., Ricciuti, B., Richardson, D. S., Weiss, J. D., Moreau, H. M., Stanhope, M. E., Afeyan, A. B., Sefton, J., McCall, W. D., Formato, E., Yang, S., Zhou, Y., Hoytema van Konijnenburg, D. P., Cole, H. L., Cordova, M., Deng, L., Rajadhyaksha, M., Quake, S. R., Awad, M. M., Chen, F., Sorger, P. K., Hodi, F. S., Rodig, S. J., Murphy, G. F., Zon, L. I.
10.1101/2024.09.18.613595 — Posted: 2024-09-19
High-throughput discovery of inhibitory protein fragments with AlphaFold
Savinov, A., Swanson, S., Keating, A. E., Li, G.-W.
10.1101/2023.12.19.572389 — Posted: 2024-09-19
Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells
Lampe, G. D., Liang, A. R., Zhang, D. J., Fernandez, I. S., Sternberg, S. H.
10.1101/2024.09.19.613948 — Posted: 2024-09-19
A neural mechanism for learning from delayed postingestive feedback
Zimmerman, C. A., Bolkan, S. S., Pan-Vazquez, A., Wu, B., Keppler, E. F., Meares-Garcia, J. B., Guthman, E. M., Fetcho, R. N., McMannon, B., Lee, J., Hoag, A. T., Lynch, L. A., Janarthanan, S. R., Lopez Luna, J. F., Bondy, A. G., Falkner, A. L., Wang, S. S.-H., Witten, I. B.
10.1101/2023.10.06.561214 — Posted: 2024-09-19
Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
Ito, M., Yun, Y., Kulkarni, D. S., Sandhu, S., Nunez, B., Hu, L., Lee, K., Lim, N., Hirota, R., Prendergast, R., Huang, C., Huang, I., Hunter, N.
10.1101/2023.11.07.566091 — Posted: 2024-09-18
Engineered Receptors for Soluble Cell-to-Cell Communication
Piraner, D. I., Abedi, M. H., Duran Gonzalez, M. J., Chazin-Gray, A., Zhu, I., Ravindran, P. T., Schlichthaerle, T., Huang, B., Lee, D., Baker, D., Roybal, K. T.
10.1101/2024.09.17.613377 — Posted: 2024-09-18

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