Channel:  Impact of Genomic Variation on Function (IGVF)

120 Articles

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
Cosgrove, B. D., Bounds, L. R., Taylor, C. K., Su, A. L., Rizzo, A. J., Barrera, A., Crawford, G. E., Hoffman, B. D., Gersbach, C. A.
10.1101/2024.01.10.574997 — Posted: 2024-01-10
Genomics 2 Proteins portal: A resource and discovery tool for linking genetic screening outputs to protein sequences and structures
Kwon, S., Safer, J., Nguyen, D. T., Hoksza, D., May, P., Arbesfeld, J., Rubin, A. F., Campbell, A. J., Burgin, A., Iqbal, S.
10.1101/2024.01.02.573913 — Posted: 2024-01-02
Rewriting regulatory DNA to dissect and reprogram gene expression
Martyn, G. E., Montgomery, M. T., Jones, H., Guo, K., Doughty, B. R., Linder, J., Chen, Z., Cochran, K., Lawrence, K. A., Munson, G., Pampari, A., Fulco, C. P., Kelley, D. R., Lander, E. S., Kundaje, A., Engreitz, J. M.
10.1101/2023.12.20.572268 — Posted: 2023-12-21
Flexible parsing, interpretation, and editing of technical sequences with splitcode
Sullivan, D. K., Pachter, L.
10.1101/2023.03.20.533521 — Posted: 2023-12-09
Reconstructing Spatial Transcriptomics at the Single-cell Resolution with BayesDeep
Jiang, X., Dong, L., Wang, S., Wen, Z., Chen, M., Xu, L., Xiao, G., Li, Q.
10.1101/2023.12.07.570715 — Posted: 2023-12-08
Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries
Weile, J., Ferra, G., Boyle, G., Pendyala, S., Amorosi, C., Yeh, C.-L., Cote, A. G., Kishore, N., Tabet, D., van Loggerenberg, W., Rayhan, A., Fowler, D. M., Dunham, M. J., Roth, F. P.
10.1101/2023.02.22.529427 — Posted: 2023-12-07
Decoding Heterogenous Single-cell Perturbation Responses
Song, B., Liu, D., Dai, W., McMyn, N., Wang, Q., Yang, D., Krejci, A., Vasilyev, A., Untermoser, N., Loregger, A., Song, D., Williams, B., Rosen, B., Cheng, X., Chao, L., Kale, H. T., Zhang, H., Diao, Y., Bürckstümmer, T., Siliciano, J. M., Li, J. J., Siliciano, R., Huangfu, D., Li, W.
10.1101/2023.10.30.564796 — Posted: 2023-11-29
MPRAbase: A Massively Parallel Reporter Assay Database
Zhao, J., Baltoumas, F. A., Konnaris, M. A., Mouratidis, I., Liu, Z., Sims, J., Agarwal, V., Pavlopoulos, G. A., Georgakopoulos-Soares, I., Ahituv, N.
10.1101/2023.11.19.567742 — Posted: 2023-11-22
Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes
Wang, Y., Armendariz, D. A., Wang, L., Zhao, H., Xie, S., Hon, G. C.
10.1101/2023.11.20.567880 — Posted: 2023-11-20
Identifying genetic variants that influence the abundance of cell states in single-cell data
Rumker, L., Sakaue, S., Reshef, Y., Kang, J. B., Yazar, S., Alquicira-Hernandez, J., Valencia, C., Lagattuta, K. A., Mah-Som, A., Nathan, A., Powell, J. E., Loh, P.-R., Raychaudhuri, S.
10.1101/2023.11.13.566919 — Posted: 2023-11-15

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