Channel:  Impact of Genomic Variation on Function (IGVF)

120 Articles

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A transient dermal niche and dual epidermal programs underlie sweat gland development
Dingwall, H. L., Tomizawa, R. R., Aharoni, A., Hu, P., Qiu, Q., Kokalari, B., Martinez, S. M., Donahue, J. C., Aldea, D., Mendoza, M., Glass, I. A., Birth Defects Research Laboratory, , Wu, H., Kamberov, Y. G.
10.1101/2023.04.15.537037 — Posted: 2023-04-17
Distinguishing biophysical stochasticity from technical noise in single-cell RNA sequencing using Monod
Gorin, G., Pachter, L.
10.1101/2022.06.11.495771 — Posted: 2023-04-17
Chromatin context-dependent regulation and epigenetic manipulation of prime editing
Li, X., Chen, W., Martin, B. K., Calderon, D., Lee, C., Choi, J., Chardon, F. M., McDiarmid, T., Kim, H., Lalanne, J.-B., Nathans, J. F., Shendure, J.
10.1101/2023.04.12.536587 — Posted: 2023-04-12
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements
Hu, Y., Ma, S., Kartha, V. K., Duarte, F. M., Horlbeck, M., Zhang, R., Shrestha, R., Labade, A., Kletzien, H., Meliki, A., Castillo, A., Durand, N., Mattei, E., Anderson, L. J., Tay, T., Earl, A. S., Shoresh, N., Epstein, C. B., Wagers, A., Buenrostro, J. D.
10.1101/2023.03.28.533945 — Posted: 2023-03-29
Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
Li, J., Jin, C., Gustafsson, S., Rao, A., Wabitsch, M., Park, C. Y., Quertermous, T., Bielczyk-Maczynska, E., Knowles, J. W.
10.1101/2023.03.27.534456 — Posted: 2023-03-29
Modeling tissue co-regulation to estimate tissue-specific contributions to disease
Amariuta, T., Siewert-Rocks, K., Price, A. L.
10.1101/2022.08.25.505354 — Posted: 2023-03-26
Accurate and Efficient Estimation of Local Heritability using Summary Statistics and LD Matrix
Li, H., Mazumder, R., Lin, X.
10.1101/2023.02.08.527759 — Posted: 2023-03-22
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions
Luo, R., Yan, J., Oh, J. W., Xi, W., Shigaki, D., Wong, W., Cho, H., Murphy, D., Cutler, R., Rosen, B. P., Pulecio, J., Yang, D., Glenn, R., Chen, T., Li, Q. V., Vierbuchen, T., Sidoli, S., Apostolou, E., Huangfu, D., Beer, M. A.
10.1101/2023.03.07.531569 — Posted: 2023-03-09
Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
Wei, Y., Zhang, E., Yu, L., Ci, B., Guo, L., Sakurai, M., Takii, S., Liu, J., Schmitz, D., Ding, Y., Zhan, L., Zheng, C., Sun, H.-X., Xu, L., Okamura, D., Ji, W., Tan, T., Wu, J.
10.1101/2023.03.07.531525 — Posted: 2023-03-08
Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
Agarwal, V., Inoue, F., Schubach, M., Martin, B., Dash, P., Zhang, Z., Sohota, A., Noble, W., Yardimci, G., Kircher, M., Shendure, J., Ahituv, N.
10.1101/2023.03.05.531189 — Posted: 2023-03-06

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