Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of alpha-synuclein inclusions
Lam, I., Ndayisaba, A., Lewis, A. J., Fu, Y., Sagredo, G. T., Zaccagnini, L., Sandoe, J., Sanz, R. L., Vahdatshoar, A., Martin, T. D., Morshed, N., Ichihashi, T., Tripathi, A., Ramalingam, N., Oettgen-Suazo, C., Bartels, T., Schabinger, M., Hallacli, E., Jiang, X., Verma, A., Tea, C., Wang, Z., Hakozaki, H., Yu, X., Hyles, K., Park, C., Theunissen, T. W., Wang, H., Jaenisch, R., Lindquist, S., Stevens, B., Stefanova, N., Wenning, G., Luk, K. C., Sanchez Pernaute, R., Gomez-Esteban, J. C., Felsky, D., Kiyota, Y., Sahni, N., Yi, S. S., Chung, C.-Y., Stahlberg, H., Ferrer, I., Schoneberg, J., Ell
10.1101/2022.11.08.515615 — Posted: 2022-12-02
Structure of LRRK1 and mechanisms of autoinhibition and activation
Reimer, J. M., Dickey, A. M., Lin, Y. X., Abrisch, R. G., Mathea, S., Chatterjee, D., Fay, E. J., Daugherty, M. D., Reck-Peterson, S. L., Leschziner, A. E.
10.1101/2022.11.22.517582 — Posted: 2022-12-02
Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Uoselis, L., Lindblom, R., Skulsuppaisarn, M., Khuu, G., Nguyen, T. N., Rudler, D. L., Filipovska, A., Schittenhelm, R. B., Lazarou, M.
10.1101/2022.11.30.518286 — Posted: 2022-11-30
Golgi-IP, a novel tool for multimodal analysis of Golgi molecular content
Fasimoye, R., Dong, W., Nirujogi, R. S., Rawat, E. S., Iguchi, M., Nyame, K., Phung, T. K., Bagnoli, E., Prescott, A. R., Alessi, D. R., Abu-remaileh, M.
10.1101/2022.11.22.517583 — Posted: 2022-11-23
Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
Ng, X. Y., Wu, Y., Lin, Y., Yaqoob, S. M., Greene, L. E., De Camilli, P., Cao, M.
10.1101/2022.02.28.482419 — Posted: 2022-11-20
Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
Dou, D., Smith, E. M., Evans, C. S., Boecker, C. A., Holzbaur, E. L. F.
10.1101/2022.11.14.516471 — Posted: 2022-11-14
Excessive Firing of Dyskinesia-Associated Striatal Direct Pathway Neurons is Gated By Dopamine and Excitatory Synaptic Input
Ryan, M. B., Girasole, A. E., McGregor, M. M., Brakaj, R., Paletzki, R. F., Gerfen, C. R., Nelson, A. B.
10.1101/2022.10.31.514594 — Posted: 2022-11-01
Association of genetic variation at the GJA5/ACP6 locus with motor progression in Parkinson's
Martinez, A., Real, R., Lawton, M., Reynolds, R. H., Tan, M. M., Wu, L., Williams, N., Carroll, C., Corvol, J.-C., Hu, M. T. M., Grosset, D., Hardy, J., shlomo, Y. B., Shoai, M., Morris, H.
10.1101/2022.10.28.22281645 — Posted: 2022-11-01
Protein aggregation and calcium dysregulation are the earliest hallmarks of synucleinopathy in human midbrain dopaminergic neurons
Virdi, G. S., Choi, M. L., Evans, J. R., Yao, Z., Athauda, D., Strohbuecker, S., Wernick, A. I., Alrashidi, H., Melandri, D., Perez-lloret, J., Stroh, P. R., Sylantyev, S., Eaton, S., Heales, S., Kunath, T., Horrocks, M. H., Abramov, A. Y., Patani, R., Gandhi, S.
10.1101/2022.10.28.514238 — Posted: 2022-10-28
Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease
Schonhoff, A. M., Figge, D. A., Jurkuvenaite, A. J., Gallups, N. J., Childers, G. M., Webster, J. A., Standaert, D. G., Goldman, J. E., Harms, A. S.
10.1101/2022.10.12.511960 — Posted: 2022-10-16

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