Channel:  Aligning Science Across Parkinson's (ASAP)

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Insights into Ancestral Diversity in Parkinsons Disease Risk: A Comparative Assessment of Polygenic Risk Scores
Saffie Awad, P., Makarious, M. B., Elsayed, I., Sanyaolu, A., Wild Crea, P., Schumacher Schuh, A. F., Levine, K. S., Vitale, D., Korestky, M. J., Kim, J., Peixoto Leal, T., Perinan, M. T., Dey, S., Noyce, A. J., Reyes-Palomares, A., Rodriguez-Losada, N., Foo, J. N., Mohamed, W., Heilbron, K., Norcliffe-Kaufmann, L., the 23andMe Research Team, , Rizig, M., Okubadejo, N., Nalls, M., Blauwendraat, C., Singleton, A., Leonard, H., Mata, I. F., Bandres Ciga, S., Global Parkinsons Genetics Program (GP2)
10.1101/2023.11.28.23299090 — Posted: 2024-05-09
The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner
Wallings, R., McFarland, K., Staley, H., Neighbarger, N., Schaake, S., Brueggemann, N., Zittel, S., Usnich, T., Klein, C., Sammler, E., Tansey, M. G.
10.1101/2023.10.12.562063 — Posted: 2024-05-02
Open-Source Platform for Kinematic Analysis of Mouse Forelimb Movement
Berezhnoi, D., Chehade, H. D., Chu, H.-Y.
10.1101/2024.01.31.578239 — Posted: 2024-04-30
A comparative analysis of Parkinson's disease and inflammatory bowel disease gut microbiomes highlights shared depletions in key butyrate-producing bacteria
Krueger, M. E., Boles, J. S., Simon, Z. D., Alvarez, S. D., McFarland, N. R., Okun, M. S., Zimmermann, E. M., Forsmark, C. E., Tansey, M. G.
10.1101/2024.04.26.591350 — Posted: 2024-04-29
Gut-Initiated Alpha Synuclein Fibrils Drive Parkinson's Disease Phenotypes: Temporal Mapping of non-Motor Symptoms and REM Sleep Behavior Disorder
Dautan, D., Paslawski, W., Montejo, S., Doyon, D., Marangiu, R., Kaplitt, M. G., Chen, R., Dawson, V. L., Zhang, X., Dawson, T. M., Svenningsson, P.
10.1101/2024.04.22.590542 — Posted: 2024-04-26
Nova-ST: Nano-Patterned Ultra-Dense platform for spatial transcriptomics
Poovathingal, S., Davie, K., Vandepoel, R., Poulvellarie, N., Verfaillie, A., Corthout, N., Aerts, S.
10.1101/2024.02.22.581576 — Posted: 2024-04-10
Kufor-Rakeb Syndrome-Associated Psychosis: A Novel Loss-of-Function ATP13A2 Variant and Response to Treatment
Colijn, M. A., Vrijsen, S., Au, P. Y., el Asrar, R. A., Houdou, M., Van den Haute, C., Sarna, J., Montgomery, G., Vangheluwe, P.
10.1101/2024.01.12.23300401 — Posted: 2024-04-10
Understanding monogenic Parkinson's disease at a global scale
Junker, J., Lange, L. M., Vollstedt, E.-J., Roopnarain, K., Doquenia, M. L. M., Ahmad-Annuar, A., Avenali, M., Bardien, S., Bahr, N., Ellis, M., Galandra, C., Gasser, T., Heutink, P., Illarionova, A., Kanana, Y., Keller Sarmiento, I. J., Kumar, K. R., Lim, S.-Y., Madoev, H., Mata, I., Mencacci, N. E., Nalls, M. A., Padmanabhan, S., Shambetova, C., Solle, J., Tan, A.-H., Trinh, J., Valente, E. M., Singleton, A., Blauwendraat, C., Lohmann, K., Fang, Z.-H., Klein, C., the Global Parkinson's Genetics Program (GP2)
10.1101/2024.03.12.24304154 — Posted: 2024-04-09
Alpha-synuclein aggregates are phosphatase resistant
Choi, S. G., Prada, D. A. G., Tittle, T., Kordower, J. H., Melki, R., Killinger, B. A.
10.1101/2023.11.20.567854 — Posted: 2024-04-09
Combined detrimental effect of male sex and GBA1 variants on cognitive decline in Parkinson's Disease
Caminiti, S. P., Avenali, M., Galli, A., Malito, R., Cuconato, G., Pilotto, A., Padovani, A., Blandini, F. P., Perani, D., Tassorelli, C., Valente, E. M.
10.1101/2024.04.02.24305191 — Posted: 2024-04-03

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