COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,695 Articles (22,913 medRxiv, 8,782 bioRxiv)

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SAMHD1 promotes SARS-CoV-2 infection by enhancing HNF1-dependent ACE2 expression in lung epithelial cells
Cheung, P.-H. H., Chan, P., Yang, H., Honne, S., Kim, B., Perlman, S., Wu, L.
10.1101/2025.10.23.684143 — Posted: 2025-10-24
Co-administration of intranasal parainfluenza virus vaccines expressing antigenically distinct SARS-CoV-2 S antigens elicits broad and durable immunity in hamsters
Park, H.-S., Matsuoka, Y., Santos, C., Duncan, E. F., Kaiser, J. A., Yang, L., Luongo, C., Liu, X., Teng, I.-T., Kwong, P. D., Buchholz, U. J., Le Nouën, C.
10.1101/2025.10.22.683849 — Posted: 2025-10-22
ADAPT-M: A workflow for rapid, quantitative in vitro measurements of enriched protein libraries
Perez, C. P., DelRosso, N. V., Noland, C. L., Parekh, U., Choe, C. A., Eguchi, R. R., Wen, Q., Fordyce, P. M., Huang, P.
10.1101/2025.10.21.683815 — Posted: 2025-10-22
Imbalanced Brain Connectome: A Novel Link between Functional Somatic Disorders, Multiple Chemical Sensitivity, and Post-COVID patients
Haghshenas Bilehsavar, S., Bonetti, L., Gleesborg, C., Juhl Lunde, S., Ovesen, T., Sigsgaard, T., Vase, L., L. Kringelbach, M., Rosengaard, A., Fink, P., Moller, A., Gormsen, L. K.
10.1101/2025.10.22.683928 — Posted: 2025-10-22
Automatic Classification of Circulating Blood Cell Clusters based on Multi-channel Flow Cytometry Imaging
Ma, S., Sengupta, S., Lee, Y., Gu, B., Chen, Y., Wang, X., Liu, Y., Xu, M., Frydman, G. H., Li, H.
10.1101/2025.10.20.683505 — Posted: 2025-10-21
Interactomics of SARS-CoV-2 Macrodomain 1 Reveals Putative Clients of ADP-ribosyl Hydrolase Activity
Cameron, C. D., Heilmann, G., Plate, L.
10.1101/2025.10.21.683784 — Posted: 2025-10-21
A Human Alveolus-on-Chip Recapitulates SARS-CoV-2-mediated Lung Injury in an Organ-relevant Context for Pre-clinical Applications
Kiener, M., De Maddalena, L. L., Roldan, N., Chouvardas, P., Froment, L., De Menna, M., Geiser, T., Stucki, J., Hobi, N., Kruithof-de Julio, M.
10.1101/2025.10.17.683096 — Posted: 2025-10-20
A cocktail of SARS-CoV-2 spike stem helix domain and receptor binding domain human monoclonal antibodies prevent the emerge of viral escape mutants
Ma, Y., Ye, C., Piepenbrink, M. S., Mahmoud, S. H., Cupic, A., Castro, E., Jackson, N., Bayoumi, M., Padron, A. S., Garcia-Sastre, A., Ippolito, G. C., Walter, M. R., Kobie, J., Martinez-Sobrido, L.
10.1101/2025.10.16.682699 — Posted: 2025-10-20
Predicting SARS-CoV-2 evolution dynamics with spatiotemporal resolution by DMS-empowered protein language model
Yang, S., Luo, X., Luo, J., Jian, F., Cao, Y.
10.1101/2025.10.17.683094 — Posted: 2025-10-20
Repeated COVID-19 vaccine boosters elicit variant-specific memory B cells in humans
Tortorici, M. A., Sprouse, K. R., Addetia, A., Brown, J. T., Harteloo, A., Elias-Warren, A., Chiu, H. Y., Veesler, D.
10.1101/2025.10.16.682893 — Posted: 2025-10-20

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).