COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,159 Articles (22,703 medRxiv, 8,456 bioRxiv)

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Recombination alters the furin cleavage site in novel bat-borne HKU5-CoV-2 coronavirus
Yeh, T.-Y., Tsai, V., Liao, S. M., Hong, C.-E., Kuo, F.-Y., Wang, Y. C., Feehley, M. C., Feehley, P. J., Lai, Y.-C., Contreras, G. P.
10.1101/2025.04.17.649446 — Posted: 2025-04-18
SM3DD with Segmented PCA: A Comprehensive Method for Interpreting 3D Spatial Transcriptomics
Blick, T., Kilgallon, A., Monkman, J., Cooper, C., Tan, C. W., Killingbeck, E., Pan, L., Kim, Y., Liang, Y., Nam, A., Leon, M., Souza-Fonseca-Guimaraes, P., Seigo Nagashima, S., Martins, A. P. C., Machado-Souza, C., De Noronha, L., Fraser, J. F., Belz, G., Souza-Fonseca-Guimaraes, F., Kulasinghe, A.
10.1101/2025.04.17.649456 — Posted: 2025-04-18
Sustained cross-species transmission of gammacoronavirus in wild birds reveled by viral characterization in China
Wang, D.-S., Zou, Y.-Y., Liu, Q., Huang, H., Han, P.-Y., Zhao, J.-Y., Zong, L.-D., Qiu, Y., Zhang, Y.-Z., Ge, X.-Y.
10.1101/2025.04.17.648926 — Posted: 2025-04-18
Longitudinal Study on Changes in COVID-19 Vaccination Intentions in Benin and Senegal: Insights from Generalized Estimating Equations (GEE)
GAYE, I., Faye, A., Ridde, V., Martin, A. E.
10.1101/2025.04.16.25325940 — Posted: 2025-04-17
Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection
Lucena Lage, S., Bricker-Holt, K., Rocco, J. M., Rupert, A., Donovan, F. X., Abramzon, Y. A., Chandrasekharappa, S. C., McNinch, C., Cook, L., Pinheiro Amaral, E., Rosenfeld, G., Dalhuisen, T., Eun, A., Hoh, R., Fehrman, E., Martin, J. N., Deeks, S. G., Henrich, T. J., Peluso, M. J., Sereti, I.
10.1101/2025.04.16.25325949 — Posted: 2025-04-17
Deletion of a KSF Motif Attenuates NSP1 Host Cell Translation Shutoff and Impairs SARS-CoV-2 Virulence
Ye, C., Ezzatpour, S., Imbiakha, B., Jackson, N., Cagatay, T., Cupic, A., Miorin, L., Choi, A., Buchholz, D. W., Carter, J., Sahler, J., Olarte-Castillo, X. A., Jager, M. C., Whittaker, G. R., August, A., Fontoura, B., Garcia-Sastre, A., Martinez-Sobrido, L., Aguilar, H. C.
10.1101/2025.04.16.649178 — Posted: 2025-04-17
Ex vivo recapitulation of intramuscular mRNA vaccination with naive and recall antigens using a human Lymphoid Follicle Chip platform
Zhai, Y., Ku, M. W., Yang, K., Patil, A., Prabhala, P., He, L., Man, Y., Spörri, S. B., Gharpure, S., Isaacs, A. R., Ferdosi, S., Pitek, A., Maruggi, G., Bertholet, S., Firestone, J., Mousavi, K., Miller, E., Luisi, K., Hellman, C. A., Williams, L. D., Tomaras, G. D., Yin, P., Gygi, S., McAuliffe, J., Ingber, D. E., Goyal, G.
10.1101/2025.04.16.649172 — Posted: 2025-04-17
Exploring Diverse Binding Mechanisms of Broadly Neutralizing Antibodies S309, S304, CYFN-1006 and VIR-7229 Targeting SARS-CoV-2 Spike Omicron Variants: Integrative Computational Modeling Reveals Balance of Evolutionary and Dynamic Adaptability in Shaping Molecular Determinants of Immune Escape
Alshahrani, M., Parikh, V., Foley, B., Verkhivker, G.
10.1101/2025.04.15.649027 — Posted: 2025-04-17
Long-lasting impact of the COVID-19 pandemic on incidence and mortality of patients hospitalized for acute heart failure: a nationwide cohort study of the entire French population from 2013 to 2023
Moulaire, P., Delory, T., Oghina, S., Damy, T., Espagnacq, M., Khlat, M., Le Coeur, S., Hejblum, G., Lapidus, N.
10.1101/2025.04.14.25325820 — Posted: 2025-04-16
Retrospective evaluation of school-related measures on pre-vaccination transmission dynamics of SARS-CoV-2
Canfora, B., Escosio, R. A., van Dorp, C. H., Boldea, O., Bonten, M., Nunes, A., Rozhnova, G.
10.1101/2025.04.14.25325720 — Posted: 2025-04-16

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).