COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,015 Articles (22,627 medRxiv, 8,388 bioRxiv)

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Leveraging Multimodal Large Language Models to Extract Mechanistic Insights from Biomedical Visuals: A Case Study on COVID-19 and Neurodegenerative Diseases
Popova, E., Jacobs, M., Hofmann-Apitius, M., Babaiha, N. S.
10.1101/2025.10.01.679928 — Posted: 2025-10-02
Memory B cell Development in Response to mRNA SARS-CoV-2 and Nanoparticle Immunization in Mice
Wiatr, m., wang, z., Canis, M., Gazumyan, A., hernandez, B., Santos, G. S., Shawraz, S., lee, S., Bieniasz, P. D., Hatziioannou, T., Muecksch, F., Nussenzweig, M. C.
10.1101/2025.10.01.679787 — Posted: 2025-10-02
Directed evolution of a stem-helix targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity
Zhou, P., Yuan, M., Zhang, Y., Limbo, O., Song, G., Zhao, F., Liu, H., He, W.-t., Capozzola, T., Callaghan, S., Avillion, G., Li, X., Beutler, N., Yong, P., Anzanello, F., Rogers, T. F., Burton, D. R., Jardine, J. G., Wilson, I. A., Andrabi, R.
10.1101/2025.10.02.680065 — Posted: 2025-10-02
Glycans modulate the adsorption of RBD Glycoproteins on polarizable surfaces
Bosch, A., Menacho, W., Perez, R., V. Guzman, H. V.
10.1101/2025.09.30.679433 — Posted: 2025-10-01
Enhanced human antigen-specific B cell responses using in vitro 3D tonsil cultures containing stromal cells
Braham, M. V. J., de Gast, M., Babii, L., Kruijer, S., Bestebroer, T. M., Richard, M., Claireaux, M., van Ham, M. S., de Wit, J., van Els, C. A. C. M., ten Brinke, A., van Gils, M.
10.1101/2025.09.30.679470 — Posted: 2025-10-01
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase
Georgiou, I., Robinson, C., O'Byrne, S., Matsuda, A., Grygier, P., Smith, C., O'Neill, S., Ahmad, S. A., Post, J. M., Groenewold, M. G., Urakova, N., Wanningen, P., Kresik, L., Plewka, J., Delpal, A., See, K., Eadsforth, T., Norval, S., Wierzbicka, K., Decroly, E., Saikatendu, K. S., Chang, E., Snijder, E. J., Pyrc, K., Czarna, A., Scott, D. E., Gilbert, I. H.
10.1101/2025.09.30.679521 — Posted: 2025-10-01
Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles Elicit Broad Antibody Responses
Dzuvor, C. K. O., Moak, S., McManus, L. R., Thomas, A., Dzordzorme, A. E., Kim, T., Joseph, J., Foley, V., Gordon, I. J., Novik, L., Holman, L. A., Dropulic, L. K., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.10.01.679649 — Posted: 2025-10-01
Plasma nirmatrelvir and molnupiravir concentrations required for inhibition of SARS CoV-2 replication differ between rhesus macaques and humans
Avila-Ponce de Leon, U., Esmaeili, S., Owens, K., Schiffer, J. T.
10.1101/2025.09.25.678525 — Posted: 2025-10-01
Approaches for estimating COVID-19 vaccine effectiveness using observational data in administrative databases: a systematic review
Chow, J. Y., Goh, Z. J., Li, R., Lim, D. Y., Wee, L. E., Lye, D. C. B., Tan, K. B., Lim, J. T.
10.1101/2025.09.29.25336864 — Posted: 2025-09-30
Longterm Impact of COVID-19 in Hospitalized and Ambulatory Jamaican Children
Mosha Miller, S. A.-P., Hicar, M. D., Berry, C.-L. S., Anderson, K. B., Lindo, J. F., Morse, G. D., Christie, C. D. C.
10.1101/2025.09.29.25335807 — Posted: 2025-09-30

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).