COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,233 Articles (22,733 medRxiv, 8,500 bioRxiv)

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The pharmacokinetics, bio-distribution and therapeutic efficacy of a trimeric nanobody against SARS-CoV-2 in the Syrian golden hamster COVID-19 model
Sharma, P., Mega, D., Kirby, A., Buckle, I., Kipar, A., Clark, J., Bentley, E., Eyssen, L., Kijak, E., Herriott, J., Sharp, J., Carroll, M. W., Owens, R., Stewart, J. P.
10.64898/2025.12.17.694727 — Posted: 2025-12-19
IGHV3-53 antibody abundance drives divergent SARS-CoV-2 immune imprinting
Niu, X., Jian, F., Li, Y., Li, K., Lei, S., Song, W., Kong, R., Cai, X., An, R., Wang, Y., Huang, Y., Yu, L., Wang, W., Sun, H., Yu, Y., Wang, J., Zhang, B., Zhu, T., Huang, J., Shao, F., Luo, S., Tan, X., Cao, Y.
10.64898/2025.12.18.694353 — Posted: 2025-12-19
Single-Particle Tracking and Positional Phenotyping Reveals Variant-Specific Early Checkpoints in SARS-CoV-2 Cell Entry
Schulz, F. H., Dreisler, M. W., Koylyu, D., Valero, J., Malle, M. G., Civit, L., Kjems, J., Hatzakis, N. S.
10.64898/2025.12.18.695048 — Posted: 2025-12-19
Patient needs and expectations regarding cognitive impairments in long COVID: perspectives of young and older adults in the UK
UK Long COVID Cognitive Experience Research Group, , Shan, D.
10.64898/2025.12.17.25342465 — Posted: 2025-12-18
Collective interactions, human mobility and viral evolution shaped the SARS-CoV-2 transmission in Mainland China
Wang, D., Wang, Y., Gressani, O., Chen, J., Tao, Y., Wang, H., Li, S., Chen, D., H. Y. Lau, E., Zhao, Y., Wu, P., Zhang, Q., Cowling, B. J., Ali, S. T.
10.64898/2025.12.17.25342513 — Posted: 2025-12-18
β-Coronavirus Nsp6 hijacks host ER translocation machineries into viral replication centers
Ecklund, K. H., Abrisch, R. G., Perlman, S., Voeltz, G. K.
10.64898/2025.12.16.694738 — Posted: 2025-12-18
SARS-CoV-2-specific immunity after XBB.1.5 vaccination is not influenced by subsequent influenza vaccination in dialysis patients
Bronder, S., Urschel, R., Reinhardt, F., Mihm, J., Schlienger, E., Schmidt, T., Brueckner, S., Sester, U., Sester, M.
10.64898/2025.12.16.25342339 — Posted: 2025-12-17
Perceptions of COVID-19 vaccination during pregnancy in CHASING COVID Cohort of US adults in 2023
Piltch-Loeb, R., Balasubramanian, S., Robertson, M., Teasdale, C., Fleary, S., Sahr, J. N., Nash, D., Penrose, K., Chan, B. X. J., Parcescepe, A.
10.64898/2025.12.15.25342316 — Posted: 2025-12-17
Oncolytic Reovirus mediates innate-driven SARS-CoV-2 elimination in the absence of cell toxicity
Garcia-Cardenas, S. Y., Swinscoe, G. e., Barningham, L. D., Cook, G. P., Samson, A., Wilson, S. J., Malim, M. M., Hughes, R. O., Griffin, S.
10.64898/2025.12.17.694833 — Posted: 2025-12-17
Rab27-dependent egress of SARS-CoV-2 via secretory amphisomes
Nijenhuis, W., Damstra, H. G. J., Van Grinsven, E. J., Praest, P., Van Grinsven, M. M. P., Soltani, Z. E., De Jong, D. C. M., Symons, J., Amatngalim, G. D., Verweij, F. J., Akhmanova, A., Nijhuis, M., Beekman, J. M., Lebbink, R. J., Kapitein, L. C.
10.64898/2025.12.15.694351 — Posted: 2025-12-16

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).