COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,948 Articles (22,604 medRxiv, 8,344 bioRxiv)

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Clinical Surveillance Identifies SARS-CoV-2 Outbreaks and Emergence of Novel Variants in Real-Time
Holland, S. C., Shoemaker, I., Rosov, T., Compton, C., LaBaer, J., Lim, E. S., Murugan, V.
10.1101/2025.09.09.25335437 — Posted: 2025-09-11
Effectiveness of 2024/25 KP.2 vaccine against outpatient COVID-19 in Canada
Separovic, L., Sabaiduc, S., Zhan, Y., Kaweski, S. E., Carazo, S., Olsha, R., Mather, R. G., Lacroix, C., Hasso, M., Levade, I., Meunier, I., Jassem, A. N., Dover, K., Gao, R., Bastien, N., Skowronski, D. M.
10.1101/2025.09.05.25335203 — Posted: 2025-09-11
Chemical modulation of the unfolded protein response reveals an antiviral role for the PERK pathway in human coronavirus 229E infection
Pellizzari-Delano, I. E., Tooley, T. H., Jani, K., Gallardo-Flores, C. E., Colpitts, C. C.
10.1101/2025.09.11.675615 — Posted: 2025-09-11
Climatic Influence on COVID-19: Investigating the Role of Temperature and Humidity in the Spread of the Omicron Variant
Lopez, L., Alfaro Checa, B., Rodo, X.
10.1101/2025.09.11.675496 — Posted: 2025-09-11
Cutaneous suction-mediated transfection in mice for delivery of DNA-encoded vaccines and proteins
Lallow, E. O., Brandtjen, I., Mo, Y., Gulley, M., Osorio, L., Kudchodkar, S., Jhumur, N. C., Roberts, C. C., Denzin, L. K., Shreiber, D. I., Parekkadan, B., Lin, H., Maslow, J. N.
10.1101/2025.09.10.675275 — Posted: 2025-09-11
Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry
Han, S., Wang, X., Li, T., Mohseni, A., Kosik, I., Chan, C. Y., Lopez-Munoz, A. D., Matthias, J., Suddaby, R., Wang, Z., Jin, A. J., Wurm, C. A., Yewdell, J. W., Wu, L.-G.
10.1101/2025.09.08.674976 — Posted: 2025-09-11
Dissecting the epigenome dynamics in human immune cells upon viral and chemical exposure by multimodal single-cell profiling
Guenduez, I. B., Wei, B., Chen, D. C., Wang, W., Hariharan, M., Norell, T., Broderick, T. J., McClain, M. T., Satterwhite, L. L., Burke, T. W., Petzold, E. A., Shen, X., Woods, C. W., Fowler, V. G., Ruffin, F., Panuwet, P., Barr, D. B., Wilk, A. J., Lee, M. J., Blish, C., Castellino, F., Walley, A. M., Evans, T., Ecker, J. R., Mueller, F., Greenleaf, W. J.
10.1101/2025.09.09.675101 — Posted: 2025-09-11
Effect of low dose naltrexone for long covid: a systematic review
Byambasuren, O., Atkins, T. J., Baptista, S., Glasziou, P., Chakraborty, S.
10.1101/2025.09.09.25335451 — Posted: 2025-09-10
Dysregulation of innate immunity and cellular metabolism through virus-induced deISGylation
Zhu, J., Liu, G., Xu, J., Li, K., Goins, C., Yu, H., Sayyad, Z., Zhou, Y., White, E., Fiehn, O., Stauffer, S., Cheng, F., Gack, M.
10.1101/2025.09.08.674928 — Posted: 2025-09-09
Cryptic spread of SARS-CoV-2 undermined targeted travel restrictions
Gangavarapu, P., Abdo, J. M., Parker, E., Zeller, M., Robles-Sikisaka, R., Kurzban, E., Perkins, S., Schwab, M., Nguyen, K., McGraw, M., Ramesh, K., Anderson, C., Rasheed, N. A., Isa, R. H., Taher, S. M., Gangavarapu, K., Andersen, K. G.
10.1101/2025.08.29.25334701 — Posted: 2025-09-08

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).