COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,757 Articles (22,943 medRxiv, 8,814 bioRxiv)

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A Structural Domain in the genomic RNA of SARS-CoV-2 Folds into a Compact Granular Structure without the N protein: A Single-Molecule Fluorescence Spectroscopic Investigation
Kimura, T., Katayama, T., Ishikawa, S., Mitra, S., Yamano, Y., Onizuka, K., Nagatsugi, F., Laha, S., Naganathan, A. N., Itoh, Y., Takahashi, S.
10.64898/2026.05.15.725307 — Posted: 2026-05-15
Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine doses
Kumar, S., Lai, L., Ellis, M., Patel, A. B., Joshi, D. J., Velden, J. V., Faraj, J. Z. A., Wimalasena, S. T., Pallavi, R. R., Iriss, J., Bechnak, K., Edupuganti, S., Rouphael, N., Ortlund, E., Moreno, A., Menachery, V. D., Zarnitsyna, V. I., Wrammert, J., Suthar, M. S.
10.64898/2026.05.13.725047 — Posted: 2026-05-15
Transcranial direct current stimulation-augmented cognitive training for post-COVID-19 cognition: A phase IIb randomized controlled trial
Trujillo Llano, C., Fromm, A. E., Lingemann, L., Grittner, U., Meinzer, M. F., Fleischmann, R., Brakemeier, E.-L., Antonenko, D. F., Floeel, A.
10.64898/2026.05.11.26352906 — Posted: 2026-05-14
Pathogen-specific host responses define distinct pneumonia endotypes in the human lung
Markov, N. S., Mozejko, M., Guggilla, V., Łazecka, M., Donnelly, H. K., Donayre, A., Fenske, S., Peltekian, A., Puczko-Szymanski, B., Szymczak, P., Izdebski, A., Luo, L., Senkow, K. J., Cusick, L., Yu, Z., Swaminathan, S., Lu, Z., Abdala-Valencia, H., Phan, D., Clepp, R. K., Rasmussen, L. V., Pawlowski, A., Pickens, C. O., Nadig, N. R., Walunas, T., Tighe, R., The Neu-Lung Investigators, , Wunderink, R. G., Budinger, G. S., Morales-Nebreda, L., Gao, C. A., Singer, B. D., Misharin, A. V., Szczurek, E., The NU SCRIPT Study Investigators
10.64898/2026.05.12.724509 — Posted: 2026-05-14
Recovery of proofreading-impaired SARS-CoV-2 reveals a mutator phenotype and an ExoN activity threshold for viability
He, L., Su, Y.-W. N., Zhang, F., Moustafa Abdelrady, I., Gohara, D. W., Ye, C., Martinez-Sobrido, L., Arnold, J. J., Cameron, C. E., Xiang, Y.
10.64898/2026.05.12.724615 — Posted: 2026-05-12
Independent Validation of Test-Adjusted COVID-19 Incidence Estimates Using Wastewater Surveillance Data in Ontario, Canada
Fisman, D., Wilson, N., Lee, C. E., Tuite, A.
10.64898/2026.05.08.26352754 — Posted: 2026-05-12
Monocyte Oxidative Stress Underlies Persistent Immune Activation in Long-COVID Postural Orthostatic Tachycardia Syndrome
Mohamed, M. A., Golchha, M., Vance, Y. A., Paranjape, S. Y., Wanjalla, C., Hunter, K. C., Dikalov, S., Diedrich, A., Kulapatana, S., Mehr, P. E., Solis Montegegro, T. X., Simmons, J. D., Harrison, D. G., Shibao, C. A.
10.64898/2026.05.08.26352776 — Posted: 2026-05-12
AI-discovered protein fragments as generalizable regulators of biomolecular condensates
Savinov, A., Sadasivan, J., White, K. J., Rubien, J. D., Li, G.-W., Case, L. B.
10.64898/2026.05.08.723928 — Posted: 2026-05-12
Crude Fucus vesiculosus fucoidan demonstrates superior SARS-CoV-2 antiviral activity compared to its pure form: binding kinetics and functional studies
Dudek, A., Janapatla, R. P., Chen, C. L., Chiu, C. H.
10.64898/2026.05.07.723385 — Posted: 2026-05-12
Temperature-Dependent Replication and Sensitivity to Innate Immunity of Human Coronavirus HKU1
Buchrieser, J., Thuillier, E., Postal, J., Wileveau, A., Guivel-Benhassine, F., Staropoli, I., Saunders, N., Planas, D., Sugrue, J., Bondet, V., Fernandez, I., Bontems, F., Porrot, F., Petiot, C., Prot, M., Jungbauer-Groznica, M., Arowas, L., Michel, V., Blanc, C., Trouillet-Assant, S., Bruel, T., Rey, F. A., Rameix-Welti, M.-A., Casartelli, N., Fontanet, A., White, M., Duffy, D., Simon-Loriere, E., Schwartz, O.
10.64898/2026.05.07.723210 — Posted: 2026-05-12

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