COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,244 Articles (22,733 medRxiv, 8,511 bioRxiv)

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Identification and characterization of a SARS-CoV-2 Mpro G23 deletion ensitrelvir-resistant mutant
Ma, Y., Ye, C., Rahisuddin, R., Mahmoud, S., Cupic, A., Khalil, A. M., Castro, E., Jackson, N., Bayoumi, M., Gupta, Y., Plemper, R. K., Martinez-Sobrido, L.
10.1101/2025.09.30.679586 — Posted: 2025-10-07
Template switching by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir
Rakib, A., Das, A., BERA, S. C., America, P., Klein, M., Anderson, T., Marecki, J. C., Wang, B. K., Bogers, E., Feng, J., Bilello, J., Papini, F. S., Smitskamp, Q., Arnold, J. J., Artsimovitch, I., Kirchdoerfer, R., Cameron, C. E., Raney, K. D., Dulin, D.
10.1101/2025.10.03.680419 — Posted: 2025-10-06
Re-infection with SARS-CoV-2 is associated with increased antibody breadth and potency against diverse sarbecovirus strains
Lilly, M., Ruiz, F., Foreman, W., Chohan, V., Guenthoer, J., Depierreux, D., Baharani, V., Ralph, D., Harteloo, A., Chu, H., Bieniasz, P. D., Starr, T., Overbaugh, J.
10.1101/2025.10.03.679858 — Posted: 2025-10-06
SARS-CoV-2 cross-reactive B-cells outnumber seasonal coronavirus spike-specific clones at the end of the COVID-19 pandemic
Gonzalez Lopez, C., Aguilar-Bretones, M., Zhang, J., Bekki, B., van den Doel, P., van Gorp, E. C., van der Kuy, P. H. M., Haagmans, B. L., GeurtsvanKessel, C. H., Koopmans, M. P. G., de Vries, R. D., van Gils, M. J., van Nierop, G. P.
10.1101/2025.09.28.25336743 — Posted: 2025-10-05
TACO: TabPFN Augmented Causal Outcomes for Early Detection of Long COVID
Pinero, S. L., Li, X., Liu, L., Li, J., Lee, S. H., Winter, M., Nguyen, T., Zhang, J., Le, T. D.
10.1101/2025.10.02.25337138 — Posted: 2025-10-05
Epidemiology and Cluster Predictions on Prevention Strategies of SARS CoV-2 Cases from 2019-2024 in Selected Districts of Zambia.
Wantakisha, E. W. R., Nyirenda, S. S., Narayani, M.
10.1101/2025.09.27.25336412 — Posted: 2025-10-05
Investigation of anti-SARS CoV-2 multimeric bicyclic peptide inhibitors in a range of pre-clinical therapeutic settings
Harman, M. A. J., Gaynor, K. U., Papa, G., Pellegrino, S., Bezerra, G. A., McGuinness, B., Jeffrey, P., Beswick, P., Stanway, S., van Rietschoten, K., Chen, L., Drulyte, I., Herriott, J., Kijak, E., Gallardo Toledo, E., Tatham, L., Sharma, P., Bentley, E., Sharp, J., Kirby, A., Owen, A., Stewart, J. P., Skynner, M. J.
10.1101/2025.10.03.680220 — Posted: 2025-10-05
Oral Microbiota Composition in Children and Adults During Spanish COVID-19 Lockdown: Impact of Home Self-Confinement and SARS-CoV-2 infection
Blanco-Fuertes, M., Gonzalez-Colomino, G., Brotons, P., Lluansi, A., Varo, R., Henares, D., Launes, C., Cisneros, M., F. de Sevilla, M., Garcia-Garcia, J.-J., Mira, A., Bassat, Q., Munoz-Almagro, C.
10.1101/2025.09.30.679491 — Posted: 2025-10-04
Vaccination inequality and social determinants in Brazil during the COVID-19 pandemic
Teixeira, R., Mouta, G. S., Cordeiro, J. S. M., Balieiro, P. C. S., Silva-Neto, A. V., Castro, D. B., Pinto, A. L. C. B., Balieiro, A. A. S., Costa, A. J. L., Sampaio, V. S.
10.1101/2025.10.01.25337110 — Posted: 2025-10-03
Rapid discovery of antiviral targets through dimensionality reduction of genome-scale metabolic models
Lee, Y.-k., Kang, S., Lim, J., Kim, K., Kim, S.-M., Casel, M. A. B., Choi, I., Choi, Y. K., Kim, H. U., Kim, Y.
10.1101/2025.10.02.679942 — Posted: 2025-10-03

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).