COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,436 Articles (22,835 medRxiv, 8,601 bioRxiv)

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Conserved phosphorylatable residues in motif G of positive-stranded virus RdRps regulate polymerase activity and suggest targets for drug design.
Duflos, C., Lizcano-Perret, B., Peersen, O., Herinckx, G., Alpizar, Y. A., Vertommen, D., Michiels, T.
10.64898/2025.12.08.692995 — Posted: 2025-12-09
A Secreted Subunit SARS-CoV-2 RBD-CpE Yeast Oral Vaccine Induces an Adaptive Immune Response in BALB/c Mice
Ramos, J. D., Bresnahan, C., Brysgel, T., Kozub, N., Mendoza, G., Murillo, L. C., Devanadera, M. K., Castillo, J., Castillo, D. A., Aguilar, J. P., Rimando, M., Austriaco, N.
10.64898/2025.12.08.692901 — Posted: 2025-12-08
The analysis of a large dataset of PCR-test results in the community reveals the impact of age, variants and vaccination status on SARS-CoV-2 viral dynamics
Beaulieu, M., Hoze, N., Vieillefond, V., Goetschy, T., Cosentino, G., Blanquart, F., Debarre, F., Guedj, J.
10.64898/2025.12.04.692282 — Posted: 2025-12-07
Serum IL-6 and IL-18 Responses in Pediatric COVID-19: Role of Vitamin D Status in a Cohort from Azerbaijan
Huseynova, I. Y., Hasanov, A. Q., Sultanova, N. H., Mammadova, F. M., Taghi-zada, T. G., Gafarov, I. A., Allahverdiyeva, A. B.
10.64898/2025.12.03.692155 — Posted: 2025-12-05
Systems Immunology of Long Covid: Insights from the STOP-PASC Clinical Trial
Maestri, E., Kwon, W. J., Zheng, H., Prestwood, T., Hedlin, H., Liang, J. W., McCann, H., Shaw, B., Tian, L., Jones, B., Lu, R., Wiley, G., Haraguchi, E., Wirz, O., Afaghani, J., Lam, B., Mahmood, D. F. D., Phillips, N. A., Sim, M. M. S., Wood, J. P., Heath, J. R., Boyd, S. D., Guthridge, J., Singh, U., Bonilla, H., Jagannathan, P., Utz, P., Geng, L. N., Khatri, P.
10.64898/2025.12.04.25341650 — Posted: 2025-12-05
Predictors of COVID-19 Vaccine Hesitancy and Adverse Events following COVID-19 vaccination among People on Anti-retroviral therapy in Nigeria
Etuk, V., Omonijo, O., Sanni, C., Ijioma, S., Abimiku, A., Okpokoro, E.
10.64898/2025.12.05.25341692 — Posted: 2025-12-05
Measurement of quality of stroke care with national electronic health records: a cohort during and after the COVID-19 pandemic
Farrell, J., Nolan, J., Lambert, R., Torralbo, A., Petersen, S. E., Hocaoglu, M., Tomlinson, C., Sofat, R., Huang, Q., Kontopantelis, E., James, M., Lessels, S., MacArthur, J. A. L., Wood, A., Whiteley, W., Denaxas, S., CVD-COVID-UK/COVID-IMPACT Consortium
10.64898/2025.12.03.25340732 — Posted: 2025-12-04
Comparative evaluation of clinical and wastewater genomic surveillance for SARS-CoV-2: implications for integrated infectious disease monitoring
Lynch, T., Lindsay, A., Croxen, M., Qureshi, A., Barnett, M., Bu, J., Chiu, T., Deo, A., Dieu, P., Dong, X., Ferrato, C., Gavriliuc, S., Getachew, F., Gill, K., Imaraj, L., Khadka, R., Koleva, P., Lee, L., Li, V., Lloyd, C., McCullough, E., Murphy, S., Naser Mohon, M. A., Obasuyi, O., Pabbaraju, K., Randhawa, N., Rotich, S., Shokoples, S., Sidig, S., Skitsko, T., Skogen, J., Trevor, H., Wong, A., Yu, C., Pang, X., Qiu, J., Marshall, N., Diggle, M., Zelyas, N., Tipples, G.
10.64898/2025.12.02.25341504 — Posted: 2025-12-04
Persistent CD4+ T cell functional deficits during recovery from prolonged symptomatic SARS-CoV-2 infection
Ziegler, J., Lawrence, C., Turner, S., Pezant, N., Redinger, N., Guthridge, C., Smith, K., Chen, J., Guthridge, J. M., James, J. A., Rankin, S. M., Thompson, L. F., Farris, A. D., Kovats, S.
10.64898/2025.12.03.692161 — Posted: 2025-12-04
The impact of COVID-19 on gastrointestinal diseases in vaccinated and unvaccinated individuals: a population-based cohort study in England
Al Arab, M., Cezard, G., Crooks, C. J., Wei, Y., Horne, E., Palmer, T. M., Coronado, J. I. C., Green, M., Fisher, L., Walker, A. J., Massey, J., Davy, S., Mehrkar, A., Bacon, S., Wood, A., Goldacre, B., Chaturvedi, N., Sterne, J. A. C., Walker, V., Denholm, R.
10.64898/2025.12.01.25341357 — Posted: 2025-12-02

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).