COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,547 Articles (22,881 medRxiv, 8,666 bioRxiv)

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Direct serological antibody discovery by integrative proteomics yields potent neutralizers overlooked by single-cell BCR sequencing
Tamara, S., van Rijswijck, D. M. H., van Rijswijk, J., Burger, J. A., Schulte, D., Moreschini, M., de Bree, G. J., van Gils, M. J., Heck, A. J. R., den Boer, M. A.
10.64898/2026.05.20.725438 — Posted: 2026-05-20
Wastewater Surveillance as an Event Detection System: Outbreak and Peak Detection of SARS-CoV-2 Across 281 U.S. Counties
Link, N. B., Garrido, R., Nande, A., Santillana, M.
10.64898/2026.05.14.26353186 — Posted: 2026-05-19
How the COVID-19 pandemic and cost-of-living crisis shaped reach and engagement in the ECAIL trial targeting socially disadvantaged families: an interdisciplinary implementation study
Poquet, D., Le Gal, C., Hincker, P., Beghin, L., Deplanque, D., Subtil, D., Sion, O., Cavalli, B., VANHOUTTE, L., Jacobsen, V., Marr, K., Sakellaris, I., de Lauzon Guillain, B., Charles, M.-A., Ley, D., Sauvegrain, P., Lioret, S.
10.64898/2026.05.14.26353230 — Posted: 2026-05-19
The SARS-CoV-2 Integrated Genomic Epidemiology Database (IGED): Linking viral genomes with patient-level metadata to advance statewide genomic surveillance in California
Ryder, R., Elder, J., Panditrao, M., Grosgebauer, K., Katz, R., Tello, L., Carroll, E., Borthwick, D., Kaur, C., Smith, R., Shiau, V., Wheeler, W., Reilly, E., Myers, J., Nelson, L., Lim, E., Arunleung, P., Baylis, E., Gilliam, S., Hennesy-Burt, T., Bregman, B., Silver, E., Kapsak, C., Wright, S., Leon, T., Bell, J., Morales, C., Wadford, D. A.
10.64898/2026.05.14.26353263 — Posted: 2026-05-19
SARS-CoV-2 Vaccination Status and MIS-C Incidence: A Systematic Review
Katherine Carroll, K., Yang, H., Mastrogiannis, A., Rojas, K., Cervia, J. S.
10.64898/2026.05.15.26353349 — Posted: 2026-05-19
Variant emergence, not vaccine deployment, drives episodic positive selection on the SARS-CoV-2 spike at provincial scale in Canada
Tomas, M., Ndongo, C. P. K., Vilain, M., Aris-Brosou, S.
10.64898/2026.05.16.725625 — Posted: 2026-05-19
Orally Bioavailable SARS-CoV-2 Protease Inhibitors Bearing a Hydroxymethyl Ketone Warhead
Elshan, N. G. R. D., Wolff, K. C., Weiss, F., Ghorai, S., Grabovyi, G., Wilson, K., Riva, L., Woods, A. K., Pedroarena, J., Nazarian, A., Liu, Y., Mazumdar, W., Song, L., Okwor, N., Malvin, J., Bakowski, M. A., Kirkpatrick, M. G., Gebara-Lamb, A., Huang, E., Nguyen-Tran, V. T. B., Chi, V., Li, S., Lee, K.-J., McNamara, C. W., Gupta, A. K., Rahimi, A., Chen, J. J., Joseph, S. B., Schultz, P. G., Chatterjee, A. K.
10.64898/2026.05.15.725542 — Posted: 2026-05-18
Environmental stochasticity can account for patterns of within-host respiratory virus evolution
Xiao, W. F., Farjo, M. N., Lowen, A. C., Koelle, K.
10.64898/2026.05.15.725410 — Posted: 2026-05-18
Who infected the reported cases? Evidence from 678,482 COVID-19 cases with identified infector collected in routine surveillance in the Netherlands, 2020-2022.
Backer, J. A., Leung, K. Y., Andeweg, S. P., Van de Kassteele, J., Veldhuijzen, I., Hahne, S., Wallinga, J.
10.64898/2026.05.15.26347859 — Posted: 2026-05-17
Expansion Revealing of Pathology Resolves Nanostructures Associated with Inflammatory Phenotypes in COVID-19 Decedent Human Brain Tissue
Stanton, A. E., Kang, J., Blanchard, J. W., Boix, C. A., Schroeder, M. E., Lee, Y., Su, H., Wang, S., Yu, E., Emenari, A., Peng, Z., Agbas, E., Cerit, O., Park, D., Zhang, R., Bennett, D. A., Yin, P., Kellis, M., Langer, R., Boyden, E., Tsai, L.-H.
10.64898/2026.05.14.725177 — Posted: 2026-05-15

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).