COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,190 Articles (22,713 medRxiv, 8,477 bioRxiv)

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Increased mannosylation of extracellular vesicles in Long COVID plasma provides a potential therapeutic target for Galanthus nivalis agglutinin (GNA) affinity resin
Pesqueira Sanchez, M. A., de Necochea Campion, R., Dalhuisen, T., Fehrman, E. A., Chhabra, P. S., Kelly, J. D., Martin, J. N., Deeks, S. G., Henrich, T. J., Peluso, M. J., LaRosa, S. P.
10.1101/2025.11.21.689519 — Posted: 2025-11-21
Antigen-reactive CD4+ T cells after SARS-CoV-2 vaccination show divergent phenotypic states with or without restimulation bias
Kocher, K., Drost, F., Schuelein, C., Spriewald, B., Schubert, B., Schober, K.
10.1101/2025.11.19.688845 — Posted: 2025-11-21
Prediction of Long COVID and Mortality among Patients with Substance Use Disorder
Wu, J., Islam, K. M. S., Madiraju, P.
10.1101/2025.11.19.25340587 — Posted: 2025-11-20
A highly divergent cryptic SARS-CoV-2 lineage exhibits strong receptor binding and immune evasion
Feng, Z., Teo, Q. W., Ibrahim, B. A., Liu, W., Zhang, D., Mao, K. J., Shao, E. K., Gregory, D. A., Wilson, I. A., Johnson, M. C., Yuan, M., Wu, N. C.
10.1101/2025.11.18.25340485 — Posted: 2025-11-20
Omicron evolution drives increased ciliated cell tropism and dysfunction in nasal epithelia.
Parry, R., Mostafavi, H., McCallum, G., Sng, J. D. J., Joensuu, M., Short, K. R., Slonchak, A., Khromykh, A.
10.1101/2025.11.19.689397 — Posted: 2025-11-20
Pathogenic IgG from long COVID patients with neurological sequelae triggers sensitive but not cognitive impairments upon transfer into mice
Mignolet, M., Deroux, C., Florkin, T., Bielarz, V., De Swert, K., Halloin, N., Sprimont, L., Ladang, A., George, F., Gilloteaux, J., Abeloos, L., Van Weyenbergh, J., Jamoulle, M., Diederich, C., Gillet, N. A., Bulpa, P., Nicaise, C.
10.1101/2025.11.20.689423 — Posted: 2025-11-20
Humoral immunity induced by LP.8.1 monovalent vaccines against a broad range of SARS-CoV-2 variants including XEC, NB.1.8.1, XFG, and BA.3.2
Kaku, Y., Fujiwara, M., Uriu, K., Yo, M. S., Kawakubo, S., Ito, J., Itoh, N., Uwamino, Y., Saito, F., Satoh, H., The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Sato, K.
10.1101/2025.11.18.689152 — Posted: 2025-11-20
A SARS-CoV-2 entry inhibitor trimerizes to lock the spike protein in a closed conformation
Mou, H., Gao, B., Ye, G., Zhang, L., Saxena, D., Bu, F., Vishwakarma, J., Zhou, S., Bayona, C. R., Li, L., Getmanenko, Y., Bhandari, J., Bailey, C. C., Crynen, G. C., Kitzmiller, C. E., Li, H., Otsuka, Y., Wang, C., Batra, L., Weston, S., Frieman, M. B., Meyerholz, D. K., Scampavia, L., Spicer, T., Harris, R. S., Cameron, M., Bannister, T., Zheng, J., Farzan, M., Li, F., Choe, H.
10.1101/2025.11.19.689107 — Posted: 2025-11-20
Risk-Based Prioritization for COVID-19 Vaccination in the Post-Emergency Phase
Yechezkel, M., Faust, J., Netzer, D., Razi-Benita, T., Shmueli, E., Arbel, R., Yamin, D.
10.1101/2025.11.18.25340522 — Posted: 2025-11-19
Impact of Climate Change, Conflict and COVID-19 Pandemic on Spatial and Temporal Trend of Cholera Outbreaks in Yobe State, Northeast Nigeria
Goni, B. W., Kwairanga, H. S., Oguntunde, O., Gana, M. L., Isiaka, M., Babagana-kyari, M., Zau, L. B., Kalil, N., Baba, M. M., Abdul, H., Fika, G. M., Bakki, B., Kida, I. M., Yusuph, H., Karimi, A., Hartig, R., Maina, M. B.
10.1101/2025.11.18.25340463 — Posted: 2025-11-19

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).