Channel:  Francis Crick Institute

1,183 Articles

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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD
Seddighi, S., Qi, Y. A., Brown, A.-L., Wilkins, O. G., Bereda, C., Belair, C., Zhang, Y., Prudencio, M., Keuss, M., Khandeshi, A., Pickles, S., Hill, S., Hawrot, J., Ramos, D., Yuan, H., Roberts, J., Kelmer Sacramento, E., Shah, S., Nalls, M. A., Colon-Mercado, J., Reyes, J., Ryan, V., Nelson, M., Cook, C., Li, Z., Screven, L., Kwan, J., Shantaraman, A., Ping, L., Koike, Y., Oskarsson, B., Staff, N., Duong, D., Ahmed, A., Secrier, M., Ule, J., Jacobson, S., Rohrer, J., Malaspina, A., Glass, J., Ori, A., Seyfried, N., Maragkakis, M., Petrucelli, L., Fratta, P., Ward, M. E.
10.1101/2023.01.23.525149 — Posted: 2023-01-23
ARPC5 deficiency leads to severe early onset systemic inflammation and early mortality
Sindram, E., Caballero-Oteyza, A., Cogata, N., Huang, S. C. M., Alizadeh, Z., Gamez-Diaz, L., Fazlollahi, M. R., Peng, X., Grimbacher, B., Way, M., Proietti, M.
10.1101/2023.01.19.524688 — Posted: 2023-01-21
Biomimetic actin cortices shape cell-sized lipid vesicles
Baldauf, L., Frey, F., Perez, M. A., Mladenov, M., Way, M., Idema, T., Koenderink, G.
10.1101/2023.01.15.524117 — Posted: 2023-01-18
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
de Jonghe, J., Kaminski, T. S., Morse, D., Tabaka, M., Ellermann, A. L., Kohler, T. N., Amadei, G., Handford, C., Findlay, G., Zernicka-Goetz, M., Teichmann, S., Hollfelder, F.
10.1101/2023.01.12.523500 — Posted: 2023-01-13
Femtosecond laser preparation of resin embedded samples for correlative microscopy workflows in life sciences
Bosch, C., Lindenau, J., Pacureanu, A., Peddie, C. J., Majkut, M., Douglas, A. C., Carzaniga, R., Rack, A., Collinson, L., Schaefer, A., Stegmann, H.
10.1101/2023.01.10.523473 — Posted: 2023-01-12
Genomic evolution of non-small cell lung cancer patient-derived xenograft models
Hynds, R. E., Huebner, A., Pearce, D. R., Akarca, A. U., Moore, D. A., Ward, S., Gowers, K. H. C., Karasaki, T., Hill, M. S., Al Bakir, M., Wilson, G. A., Pich, O., Sivakumar, M., Ben Aissa, A., Gronroos, E., Chandrasekharan, D., Kolluri, K. K., Towns, R., Wang, K., Cook, D. E., Bosshard-Carter, L., Naceur-Lombardelli, C., Rowan, A. J., Veeriah, S., Litchfield, K., Quezada, S. A., Janes, S. M., Jamal-Hanjani, M., Marafioti, T., TRACERx Consortium, , McGranahan, N., Swanton, C.
10.1101/2023.01.06.521078 — Posted: 2023-01-06
Control of atypical PKC{iota} membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface
Cobbaut, M., McDonald, N. Q., Parker, P. J.
10.1101/2023.01.03.522491 — Posted: 2023-01-04
Optimization of energy production and central carbon metabolism in a non-respiring eukaryote
Alam, S., Gu, Y., Reichert, P., Bahler, J., Oliferenko, S.
10.1101/2022.12.29.522219 — Posted: 2022-12-29
Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins
Franck, C., Patel, K., Walport, L. J., Christie, M. T., Norman, A., Passioura, T., Payne, R. J., Suga, H., Mackay, J. P.
10.1101/2022.12.25.521885 — Posted: 2022-12-26
Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
Ramirez Montero, D., Sanchez, H., van Veen, E., van Laar, T., Solano, B., Diffley, J. F. X., Dekker, N. H.
10.1101/2022.12.23.521684 — Posted: 2022-12-23

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