Channel: Francis Crick Institute

1,188 Articles

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Genomic evolution of non-small cell lung cancer patient-derived xenograft models

Hynds, R. E., Huebner, A., Pearce, D. R., Akarca, A. U., Moore, D. A., Ward, S., Gowers, K. H. C., Karasaki, T., Hill, M. S., Al Bakir, M., Wilson, G. A., Pich, O., Sivakumar, M., Ben Aissa, A., Gronroos, E., Chandrasekharan, D., Kolluri, K. K., Towns, R., Wang, K., Cook, D. E., Bosshard-Carter, L., Naceur-Lombardelli, C., Rowan, A. J., Veeriah, S., Litchfield, K., Quezada, S. A., Janes, S. M., Jamal-Hanjani, M., Marafioti, T., TRACERx Consortium, , McGranahan, N., Swanton, C.

10.1101/2023.01.06.521078 — Posted: 2023-01-06

Control of atypical PKC{iota} membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface

Cobbaut, M., McDonald, N. Q., Parker, P. J.

10.1101/2023.01.03.522491 — Posted: 2023-01-04

Optimization of energy production and central carbon metabolism in a non-respiring eukaryote

Alam, S., Gu, Y., Reichert, P., Bahler, J., Oliferenko, S.

10.1101/2022.12.29.522219 — Posted: 2022-12-29

Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins

Franck, C., Patel, K., Walport, L. J., Christie, M. T., Norman, A., Passioura, T., Payne, R. J., Suga, H., Mackay, J. P.

10.1101/2022.12.25.521885 — Posted: 2022-12-26

Cleavage furrow-directed cortical flows bias mechanochemical pathways for PAR polarization in the C. elegans germ lineage

Ng, K., Hirani, N., Bland, T., Pinto, J. B., Goehring, N. W.

10.1101/2022.12.22.521633 — Posted: 2022-12-23

Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation

Ramirez Montero, D., Sanchez, H., van Veen, E., van Laar, T., Solano, B., Diffley, J. F. X., Dekker, N. H.

10.1101/2022.12.23.521684 — Posted: 2022-12-23

Back to the Future: Unleashing your cytometers spectral potential

Walker, R. V., Hall, C., Ibrahim, H., Thompson, S., Hobson, P., Crofts, J.-A., Nobes, P., Lim, S., Burpee, T.

10.1101/2022.12.21.521417 — Posted: 2022-12-22

Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species

Trejo-Reveles, V., Owen, N., Chan, B. H. C., Toms, M., Schoenebeck, J. J., Moosajee, M., Rainger, J.

10.1101/2022.12.22.521600 — Posted: 2022-12-22

The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes

Barreiro, R. A. S., Guardia, G. D. A., Meliso, F. M., Lei, X., Savio, A., Fellermeyer, M., Conceicao, H. B., Mercuri, R. L. V., Landry, T., Qiao, M., Blazquez, L., Ule, J., Penalva, L. O., Galante, P. A. F.

10.1101/2022.12.20.521107 — Posted: 2022-12-20

Quantitative drug susceptibility testing for M. tuberculosis using unassembled sequencing data and machine learning

The CRyPTIC consortium, , Lachapelle, A. S.

10.1101/2021.09.14.458035 — Posted: 2022-12-19

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