Channel:  Francis Crick Institute

1,137 Articles

H4K16ac activates transcription of transposable elements and contribute to their cis regulatory function
Pal, D., Patel, M., Boulet, F., Sundarraj, J., Grant, O. A., Branco, M. R., Basu, S., Santos, S., Zabet, N. R., Scaffidi, P., Pradeepa, M. M.
10.1101/2022.04.29.488986 — Posted: 2022-11-16
Structural basis for ubiquitylation by HOIL-1
Wu, Q., Koliopoulos, M. G., Rittinger, K., Stieglitz, B.
10.1101/2022.11.13.516300 — Posted: 2022-11-13
Orexin cells efficiently decode blood glucose dynamics to drive adaptive behavior
Viskaitis, P., Tesmer, A., Karnani, M. M., Arnold, M., Donegan, D., Bracey, E., Grujic, N., Peleg-Raibstein, D., Burdakov, D.
10.1101/2022.04.14.488310 — Posted: 2022-11-09
Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier
Hu, X., Xiao, W., Lei, Y., Green, A. J., Li, X., Maradana, M. R., Gao, Y., Xie, X., Wang, R., Chennell, G., Basson, M. A., Kille, P., Maret, W., Bewick, G., Zhou, Y., Hogstrand, C.
10.1101/2022.11.03.515052 — Posted: 2022-11-04
An improved Erk biosensor reveals oscillatory Erk dynamics driven by mitotic erasure during early development
Wilcockson, S. G., Guglielmi, L., Araguas Rodriguez, P., Amoyel, M., Hill, C. S.
10.1101/2022.11.03.515001 — Posted: 2022-11-04
Intracellular calcium elevations drive the nucleation of FIP200- and ATG13-containing pre-autophagosomal structures that become omegasomes
Smith, M., Schoenfelder, P., Manifava, M., Polson, H., Tooze, S., Roderick, L., Ktistakis, N.
10.1101/2022.11.02.514842 — Posted: 2022-11-02
Protein aggregation and calcium dysregulation are the earliest hallmarks of synucleinopathy in human midbrain dopaminergic neurons
Virdi, G. S., Choi, M. L., Evans, J. R., Yao, Z., Athauda, D., Strohbuecker, S., Wernick, A. I., Alrashidi, H., Melandri, D., Perez-lloret, J., Stroh, P. R., Sylantyev, S., Eaton, S., Heales, S., Kunath, T., Horrocks, M. H., Abramov, A. Y., Patani, R., Gandhi, S.
10.1101/2022.10.28.514238 — Posted: 2022-10-28
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion
Lin, J. Q., Khuperkar, D., Pavlou, S., Makarchuk, S., Patikas, N., Lee, F. C. Y., Kang, J., Field, S. F., Zbiegly, J. M., Freeman, J. L., Ule, J., Metzakopian, E., Ruepp, M.-D., Mallucci, G. R.
10.1101/2022.10.27.514062 — Posted: 2022-10-27
Blood and site of disease inflammatory profiles differ in HIV-1-infected pericardial tuberculosis patients
Mutavhatsindi, H., Du Bruyn, E., Ruzive, S., Howlett, P., Sher, A., Mayer-Barber, K. D., Barber, D. L., Ntsekhe, M., Wilkinson, R. J., Riou, C.
10.1101/2022.10.21.513232 — Posted: 2022-10-24
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation
Altea-Manzano, P., Doglioni, G., Cuadros, A. M., Nolan, E., Fernandez-Garcia, J., Wu, Q., Cidre-Aranaz, F., Montagne, A., Planque, M., Marin-Bejar, O., Van Elsen, J., Vermeire, I., Broekaert, D., Riera-Domingo, C., Richard, F., Geukens, T., De Schepper, M., Leduc, S., Hatse, S., Lambrechts, Y., Kay, E., Lilla, S., Demeyer, S., Geldhof, V., Boeckx, B., Alekseenko, A., de la Calle Arregui, C., Floris, G., Marine, J.-C., Lambrechts, D., Pelechano, V., Mazzone, M., Zanivan, S., Cools, J., Wildiers, H., Baud, V., Gruenewald, T. G. P., Desmedt, C., Malanchi, I., Fendt, S.-M.
10.1101/2022.10.24.513556 — Posted: 2022-10-24

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