Channel:  Francis Crick Institute

1,139 Articles

ChromWave: Deciphering the DNA-encoded competition between transcription factors and nucleosomes with deep neural networks
Cakiroglu, S. A., Steinhauser, S., Smith, J., Xing, W., Luscombe, N. M.
10.1101/2021.03.19.436198 — Posted: 2023-02-13
Unique Amphipathic α-helix Drives Membrane Insertion and Enzymatic Activity of ATG3
Nishimura, T., Lazzeri, G., Mizushima, N., Covino, R., Tooze, S.
10.1101/2023.02.11.528101 — Posted: 2023-02-12
The ecdysone receptor promotes or suppresses proliferation according toligand level
Perez-Mockus, G., Cocconi, L., Alexandre, C., Aerne, B. L., Salbreux, G., Vincent, J.-P.
10.1101/2023.02.10.527985 — Posted: 2023-02-11
A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Ong, H. W., Liang, Y., Richardson, W., Lowry, E. R., Wells, C. I., Chen, X., Silvestre, M., Dempster, K., Silvaroli, J. A., Smith, J. L., Wichterle, H., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Drewry, D., Axtman, A. D.
10.1101/2023.02.09.527935 — Posted: 2023-02-11
A low-cost device for cryoanesthesia of neonatal rodents
Jamieson, B. B., Konstantinou, G., Cano-Ferrer, X., de Launoit, E., Renier, N., Imbert, A., Kohl, J.
10.1101/2022.06.09.495437 — Posted: 2023-02-09
Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
Tomic, G., Sheridan, C., Refermat, A. Y., Baggelaar, M. P., Sipthorp, J., Sudarshan, B., Ocasio, C. A., Suarez-Bonnet, A., Priestnall, S. L., Herbert, E., Tate, E. W., Downward, J.
10.1101/2023.02.08.527637 — Posted: 2023-02-09
Enzyme-less nanopore detection of post-translational modifications within long polypeptides
Martin-Baniandres, P., Lan, W.-H., Board, S., Romero-ruiz, M., Garcia-Manyes, S., Qing, Y., Bayley, H.
10.1101/2023.02.09.527483 — Posted: 2023-02-09
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M., Baltussen, L. L., Lopes, A. T., Qiu, Y., Sirvio, L., Mihaylov, S. R., Claxton, S., Richardson, J. C., Lignani, G., Ultanir, S. K.
10.1101/2022.11.24.517538 — Posted: 2023-02-08
Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Caswell, D. R., Mayekar, M. K., Gui, P., Law, E. K., Vokes, N. I., Ruiz, C. M., Dietzen, M., Angelova, M., Bailey, C., Pich, O., Bakker, B., Wu, W., Humpton, T. J., Kerr, D. L., Hill, W., Lu, W.-T., Haderk, F., Blakely, C. M., Bakir, M. A., Nagano, A., Gimeno-Valiente, F., Weeden, C., Rowan, A., McCoach, C. E., Almeida, B., Green, M., Gomez, C., Gini, B., Nanjo, S., Barbosa, D., Moore, C., Przewrocka, J., Gronroos, E., Priestnall, S., Suarez-Bonnet, A., Zverev, C., Lighterness, S., Cormack, J., Olivas, V., Cech, L., Rule, B., Ashford, P., Durfee, C., Temiz, N. A., Tan, L., Larson, L. K., Argyr
10.1101/2020.12.18.423280 — Posted: 2023-02-05
PerTurboID: A targeted in situ method to measure changes in a local protein environment reveals the impact of kinase deletion on cytoadhesion in malaria causing parasites
Davies, H., Belda, H., Broncel, M., Dalimot, J., Treeck, M.
10.1101/2023.02.02.526785 — Posted: 2023-02-03

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