Channel:  Francis Crick Institute

1,203 Articles

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SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
Dembitz, V., Lawson, H., Burt, R., Philippe, C., James, S. C., Atkinson, S., Durko, J., Wang, L. M., Campos, J., Magee, A. M., Woodley, K., Austin, M. J., Rio-Machin, A., Casado-Izquierdo, P., Bewicke-Copley, F., Rodriguez, G., Pereira, D., Oudejans, L., Boet, E., von Kriegsheim, A., Schwaller, J., Finch, A. J., Pate, B., Sarry, J.-E., Tamburini, J., Schuringa, J. J., Hazlehurst, L., Copland, J. A., Yuneva, M., Peck, B., Cutillas, P., Fitzgibbon, J., Rouault-Pierre, K., Kranc, K., Gallipoli, P.
10.1101/2023.08.02.551656 — Posted: 2023-09-04
Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Zou, D., Morin, G., Pacis, A., Yang, Y., Martinez, C., Barber, J., Kuasne, H., Li, R., Bourgey, M., Fortier, A.-M., Davison, P. G., Omeroglu, A., Guiot, M. C., Morris, Q., Kleinman, C. L., Huang, S., Gingras, A.-C., Ragoussis, I., Bourque, G., Van Loo, P., Park, M.
10.1101/2023.06.10.544434 — Posted: 2023-09-02
Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity
Montorsi, L., Pitcher, M. J., Zhao, Y., Demonti, A., Tull, T. J., Dionisi, C., Dhami, P., Ellis, R. J., Bishop, C., Sanderson, J., Jain, S., D'Cruz, D., Gibbons, D., Winkler, T. H., Bemark, M., Ciccarelli, F. D., Spencer, J.
10.1101/2023.08.29.555265 — Posted: 2023-08-31
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Chan, A. W., Broncel, M., Yifrach, E., Haseley, N. R., Chakladar, S., Andree, E., Herneisen, A. L., Shortt, E., Treeck, M., Lourido, S.
10.1101/2023.01.11.523553 — Posted: 2023-08-29
Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
Capitanchik, C., Ireland, S., Harston, A., Cheshire, C., Jones, D. M., Lee, F. C. Y., Ruiz de los Mozos, I., Iosub, I. A., Kuret, K., Faraway, R., Wilkins, O. G., Arora, R., Hallegger, M., Modic, M., Chakrabarti, A. M., Luscombe, N. M., Ule, J.
10.1101/2023.08.22.544179 — Posted: 2023-08-29
Defective cytoskeletal dynamics underlies the essential role of MRTF-SRF in IL-2 delivery to CD8+ T cells during infectious challenge
Maurice, D., Costello, P., Gualdrini, F., Frederico, B., Treisman, R.
10.1101/2023.08.26.554941 — Posted: 2023-08-27
FOXL2 interaction with different binding partners regulates the dynamics of ovarian development
Migale, R., Neumann, M., Mitter, R., Rafiee, M.-R., Wood, S., Olsen, J., Lovell-Badge, R.
10.1101/2023.04.14.536403 — Posted: 2023-08-24
Mutual homeostasis of charged proteins
Faraway, R., Heaven, N. C., Digby, H., Wilkins, O. G., Chakrabarti, A. M., Iosub, I. A., Knez, L., Ameres, S. L., Plaschka, C., Ule, J.
10.1101/2023.08.21.554177 — Posted: 2023-08-21
CRISPR/Cas9 screen identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer
Boumelha, J., de Castro, A., Bah, N., Cha, H., de Carne Trecesson, S., Rana, S., Anastasiou, P., Mugarza, E., Moore, C., Goldstone, R., East, P., Litchfield, K., Lee, S.-H., Molina-Arcas, M., Downward, J.
10.1101/2023.04.13.536740 — Posted: 2023-08-17
Automated staging of zebrafish embryos with deep learning
Jones, R. A., Renshaw, M. J., Devenport, D., Barry, D. J.
10.1101/2023.01.13.523922 — Posted: 2023-08-17

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