Channel : Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

494 Articles

USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma
Ruiz, E. J., Pinto-Fernandez, A., Turnbull, A. P., Lan, L., Charlton, T. M., Scott, H. C., Damianou, A., Vere, G., Riising, E. M., Da Costa, C., Krajewski, W. W., Guerin, D., Kearns, J., Ioannidis, S., Katz, M., McKinnon, C., O'Connell, J. C., Moncaut, N., Rosewell, I., Nye, E., Jones, N., Heride, C., Gersch, M., Wu, M., Dinsmore, C. J., Hammonds, T. R., Kim, S., Komander, D., Urbe, S., Clague, M. J., Kessler, B. M., Behrens, A.
10.1101/2020.11.17.377705 — Posted: 2020-12-30
Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation
Blassberg, R., Patel, H., Watson, T., Gouti, M., Metzis, V., Delas, J., Briscoe, J.
10.1101/2020.12.29.424684 — Posted: 2020-12-30
Wnt/beta-catenin signalling is dispensable for adult neural stem cell homeostasis and activation.
Austin, S. H. L., Harris, L., Paun, O., Rigo, P., Guillemot, F., Urban Avellaneda, N.
10.1101/2020.12.29.424694 — Posted: 2020-12-29
Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism
Pospori, C., Grey, W., Gonzalez-Anton, S., Gibson, S. V., Georgiou, C., Birch, F., Stevens, G., Williams, T., Khorshed, R., Haltalli, M. L. R., Skoufou-Papoutsaki, M.-N., Sloan, K., Encabo, H. H., Hopkins, J., Christodoulidou, C., Stampoulis, D., Hearn-Yates, F., Gribben, J., Stauss, H. J., Chakraverty, R., Bonnet, D., Lo Celso, C. L.
10.1101/2020.12.21.414649 — Posted: 2020-12-22
APOBEC3B expression generates an immunogenic model of Kras mutant lung cancer
de Carne Trecesson, S., Boumelha, J., Law, E., Romero-Clavijo, P., Mugarza, E., Coelho, M., Moore, C., Rana, S., Caswell, D., Murillo, M., Hancock, D., Argyris, P., Brown, W., Durfee, C., Larson, L., Vogel, R., Alejandro Suarez-Bonnet, A., Priestnall, S., East, P., Ross, S., Molina-Arcas, M., Swanton, C., Harris, R., Downward, J.
10.1101/2020.12.22.423126 — Posted: 2020-12-22
Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Mayekar, M. K., Caswell, D. R., Vokes, N. I., Law, E. K., Wu, W., Hill, W., Gronroos, E., Rowan, A., Al Bakir, M., McCoach, C. E., Blakely, C. M., Temiz, N. A., Nagano, A., Kerr, D. L., Rotow, J. K., Haderk, F., Dietzen, M., Ruiz, C. M., Almeida, B., Cech, L., Gini, B., Przewrocka, J., Moore, C., Murillo, M., Bakker, B., Rule, B., Durfee, C., Nanjo, S., Tan, L., Larson, L. K., Argyris, P. P., Brown, W. L., Yu, J., Gomez, C., Gui, P., Vogel, R. I., Yu, E. A., Thomas, N. J., Venkatesan, S., Hobor, S., Chew, S. K., Kanu, N., McGranahan, N., Van Allen, E. M., Downward, J., Harris, R. S., Bivona, T
10.1101/2020.12.18.423280 — Posted: 2020-12-21
Free recall scaling laws and short-term memory effects in a latching attractor network
Boboeva, V., Pezzotta, A., Clopath, C.
10.1101/2020.12.19.423464 — Posted: 2020-12-21
Molecular fluctuations as a ruler of force-induced protein conformations
Stannard, A., Mora, M., Beedle, A. E. M., Castro-Lopez, M., Board, S., Garcia-Manyes, S.
10.1101/2020.12.18.423481 — Posted: 2020-12-19
Longitudinal omics in Syrian hamsters integrated with human data unravel complexity of moderate immune responses to SARS-CoV-2
Nouailles, G., Wyler, E., Pennitz, P., Postmus, D., Vladimirova, D., Kazmierski, J., Pott, F., Dietert, K., Mülleder, M., Farztdinov, V., Obermayer, B., Wienhold, S.-M., Andreotti, S., Höfler, T., Sawitzki, B., Drosten, C., Sander, L. E., Suttorp, N., Ralser, M., Beule, D., Gruber, A. D., Goffinet, C., Landthaler, M., Trimpert, J., Witzenrath, M.
10.1101/2020.12.18.423524 — Posted: 2020-12-19
KLF17 promotes human naïve pluripotency but is not required for its establishment
Lea, R. A., McCarthy, A., Boeing, S., Niakan, K. K.
10.1101/2020.12.18.423466 — Posted: 2020-12-18

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