Channel: Francis Crick Institute

1,236 Articles

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Eosinophils are an integral component of the pulmonary granulocyte response in Tuberculosis and promote host resistance in mice

Bohrer, A. C., Castro, E., Hu, Z., Queiroz, A. T. L., Tocheny, C. E., Assmann, M., Sakai, S., Nelson, C., Baker, P. J., Ma, H., Wang, L., Zilu, W., du Bruyn, E., Riou, C., Kauffman, K. D., Tuberculosis Imaging Program, , Moore, I. N., Del Nonno, F., Petrone, L., Goletti, D., Martineau, A. R. R., Lowe, D. M., Cronan, M. R., Wilkinson, R. J., Barry, C. E., Via, L. E., Barber, D. L., Klion, A. D., Andrade, B. B., Song, Y., Wong, K.-W., Mayer-Barber, K. D.

10.1101/2021.05.29.446277 — Posted: 2021-05-31

Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25

Haubrich, K., Augsten, S., Alvarez, L., Huppertz, I., Simon, B., Perez, K., Masiewicz, P., Lethier, M., Rittinger, K., Gabel, F., Hentze, M. W., Cusack, S., Hennig, J.

10.1101/2020.05.04.070177 — Posted: 2021-05-30

Neural stem cells alter nucleocytoplasmic partitioning and accumulate nuclear polyadenylated transcripts during quiescence

Rossi, A., Coum, A., Madelenat, M., Harris, L., Miedzik, A., Strohbuecker, S., Chai, A., Fiaz, H., Chaouni, R., Faull, P., Grey, W., Bonnet, D., Hamid, F., Makeyev, E. V., Snijders, A. P., Kelly, G., Guillemot, F., Sousa-Nunes, R.

10.1101/2021.01.06.425462 — Posted: 2021-05-29

Notch controls the cell cycle to define leader versus follower identities during collective cell migration.

Alhashem, Z., Feldner-Busztin, D., Revell, C., Alvarez-Garcillan Portillo, M., Richardson, J., Rocha, M., Gauert, A., Corbeaux, T., Prince, V. E., Bentley, K., Linker, C.

10.1101/2021.05.27.445572 — Posted: 2021-05-27

Automatic instance segmentation of mitochondria in electron microscopy data

Nightingale, L., de Folter, J., Spiers, H., Strange, A., Collinson, L. M., Jones, M. L.

10.1101/2021.05.24.444785 — Posted: 2021-05-24

SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease

Tapia del Fierro, A., den Hamer, B., Jansz, N., Chen, K., Beck, T., Vanyai, H., Benetti, N., Gurzau, A. D., Daxinger, L., Xue, S., Nguyen Ly, T. T., Wanigasuriya, I., Breslin, K., Oey, H., Krom, Y., van der Hoorn, D., Bouwman, L. F., Ritchie, M. E., Reversade, B., Prin, F., Mohun, T., van der Maarel, S. M., McGlinn, E., Murphy, J. M., Keniry, A., de Greef, J. C., Blewitt, M. E.

10.1101/2021.05.12.443934 — Posted: 2021-05-18

Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22

Schnepf, D., Hernandez, P., Mahlakoiv, T., Crotta, S., Sullender, M. E., Peterson, S. T., Ohnemus, A., Michiels, C., Gentle, I., Dumoutier, L., Reis, C. A., Diefenbach, A., Wack, A., Baldridge, M. T., Staeheli, P.

10.1101/2021.02.18.431818 — Posted: 2021-05-18

Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity

Prieto-Godino, L. L., Schmidt, H. R., Benton, R.

10.1101/2021.04.23.440888 — Posted: 2021-05-14

The Aspartyl Protease Ddi1 Is Essential for Erythrocyte Invasion by the Malaria Parasite

Ridewood, S., Dirac-Svejstrup, B., Howell, S. A., Weston, A., Lehmann, C., Patel, A. P., Collinson, L., Bingham, R., Powell, D., Snijder, A., Svejstrup, J. Q., Deu, E.

10.1101/2021.05.11.443575 — Posted: 2021-05-11

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

Geijer, M., Zhou, D., Selvam, K., Steurer, B., Evers, B., Mukherjee, C., Cugusi, S., van Toorn, M., van der Woude, M., Gong, W., Janssens, R., Raams, A., Lebbink, J., Geverts, B., Plummer, D., Bezstarosti, K., Theil, A., Mitter, R., Houtsmuller, A., Vermeulen, W., Demmers, J., Li, S., Lans, H., Bernards, R., Svejstrup, J., Ray Chaudhuri, A., Wyrick, J., Marteijn, J.

10.1101/2021.05.11.443558 — Posted: 2021-05-11

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