Channel:  Francis Crick Institute

1,159 Articles

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Schizosaccharomyces versatilis represents a distinct evolutionary lineage.
Etherington, G. J., Gomez Gil, E., Haerty, W., Oliferenko, S., Nieduszynski, C.
10.1101/2023.09.04.556188 — Posted: 2023-09-19
Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A
Lana-Elola, E., Aoidi, R., Llorian, M., Gibbins, D., Buechsenschuetz, C., Bussi, C., Flynn, H., Gilmore, T., Watson-Scales, S., Haugsten Hansen, M., Hayward, D., Song, O.-R., Brault, V., Herault, Y., Deau, E., Meijer, L., Snijders, A., Gutierrez, M., Fisher, E., Tybulewicz, V.
10.1101/2023.09.18.558244 — Posted: 2023-09-19
Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features
Etherington, G. J., Wu, P.-S., Oliferenko, S., Uhlmann, F., Nieduszynski, C.
10.1101/2023.09.04.556195 — Posted: 2023-09-19
Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis
Alvarez-Martinez, M., Cox, L. S., Pearson, C. F., Branchett, W. J., Chakravarty, P., Wu, X., Slawinski, H., Al Dibouni, A., Samelis, V., Gabrysova, L., Priestnall, S. L., Suarez-Bonnet, A., Mikolajczak, A., Briscoe, J., Powrie, F., O'Garra, A.
10.1101/2023.09.14.557705 — Posted: 2023-09-16
GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation
Grimm, F., Asuaje, A., Jain, A., Silva dos Santos, M., Kleinjung, J., Nunes, P. M., Gehrig, S., Fets, L., MacRae, J., Anastasiou, D.
10.1101/2023.09.06.556522 — Posted: 2023-09-08
The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes
Raguseo, F., Huyghebaert, A., Li, J., Balendra, R., Petric Howe, m., Wang, Y., Vadukul, D. M., Tanase, D., Maher, T. E., Malouf, L., Rubio Sanchez, R., Aprile, F. A., Elani, Y., Patani, R., Di Michele, L., Di Antonio, M.
10.1101/2023.01.31.526399 — Posted: 2023-09-04
SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
Dembitz, V., Lawson, H., Burt, R., Philippe, C., James, S. C., Atkinson, S., Durko, J., Wang, L. M., Campos, J., Magee, A. M., Woodley, K., Austin, M. J., Rio-Machin, A., Casado-Izquierdo, P., Bewicke-Copley, F., Rodriguez, G., Pereira, D., Oudejans, L., Boet, E., von Kriegsheim, A., Schwaller, J., Finch, A. J., Pate, B., Sarry, J.-E., Tamburini, J., Schuringa, J. J., Hazlehurst, L., Copland, J. A., Yuneva, M., Peck, B., Cutillas, P., Fitzgibbon, J., Rouault-Pierre, K., Kranc, K., Gallipoli, P.
10.1101/2023.08.02.551656 — Posted: 2023-09-04
Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Zou, D., Morin, G., Pacis, A., Yang, Y., Martinez, C., Barber, J., Kuasne, H., Li, R., Bourgey, M., Fortier, A.-M., Davison, P. G., Omeroglu, A., Guiot, M. C., Morris, Q., Kleinman, C. L., Huang, S., Gingras, A.-C., Ragoussis, I., Bourque, G., Van Loo, P., Park, M.
10.1101/2023.06.10.544434 — Posted: 2023-09-02
Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity
Montorsi, L., Pitcher, M. J., Zhao, Y., Demonti, A., Tull, T. J., Dionisi, C., Dhami, P., Ellis, R. J., Bishop, C., Sanderson, J., Jain, S., D'Cruz, D., Gibbons, D., Winkler, T. H., Bemark, M., Ciccarelli, F. D., Spencer, J.
10.1101/2023.08.29.555265 — Posted: 2023-08-31
Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
Capitanchik, C., Ireland, S., Harston, A., Cheshire, C., Jones, D. M., Lee, F. C. Y., Ruiz de los Mozos, I., Iosub, I. A., Kuret, K., Faraway, R., Wilkins, O. G., Arora, R., Hallegger, M., Modic, M., Chakrabarti, A. M., Luscombe, N. M., Ule, J.
10.1101/2023.08.22.544179 — Posted: 2023-08-29

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