Channel:  Francis Crick Institute

1,159 Articles

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Oncogenic PIK3CA corrupts growth factor signaling specificity
Madsen, R. R., Le Marois, A., Mruk, O., Voliotis, M., Yin, S., Sufi, J., Qin, X., Zhao, S. J., Gorczynska, J., Morelli, D., Davidson, L., Sahai, E., Korolchuk, V. I., Tape, C. J., Vanhaesebroeck, B.
10.1101/2023.12.23.573207 — Posted: 2023-12-26
Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice
King, A., Reichl, P., Metson, J. S., Parker, R., Munro, D., Oliveira, C., Becker, J. R., Biggs, D., Preece, C., Davies, B., Chapman, J. R.
10.1101/2023.12.20.572534 — Posted: 2023-12-21
Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M., Bentham, R. B., Henriques, T., Ng, S. Q., Ren, Z., Esculier, C., Agarwal, S., Tong, E., Ilangovan, S., Szabadkai, Z., Suman, M., Patani, N., Ghanate, A., Bryson, K., Stein, R. C., Yuneva, M., Szabadkai, G.
10.1101/2023.02.17.528922 — Posted: 2023-12-21
RASP: Optimal single fluorescent puncta detection in complex cellular backgrounds
Fu, B., Brock, E. E., Andrews, R., Breiter, J. C., Tian, R., Toomey, C. E., Lachica, J., Lashley, T., Ryten, M., Wood, N. W., Vendruscolo, M., Gandhi, S., Weiss, L. E., Beckwith, J. S., Lee, S. F.
10.1101/2023.12.18.572148 — Posted: 2023-12-19
The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
Timimi, L., Wrobel, A. G., Chiduza, G. N., Maslen, S. L., Torres-Mendez, A., Montaner, B., Davis, C., Skehel, M., Rubinstein, J. L., Schreiber, A. L., Beale, R.
10.1101/2023.12.19.572309 — Posted: 2023-12-19
Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography
Greenwood, H. E., Edwards, R. S., Tyrrell, W. E., Barber, A. R., Baark, F., Tanc, M., Khalil, E., Falzone, A., Ward, N. P., DeBlasi, J. M., Torrente, L., Pearce, D. R., Firth, G., Smith, L. M., Vilhelmsson Timmermand, O., Huebner, A., George, M. E., Swanton, C., Hynds, R. E., DeNicola, G. M., Witney, T. H.
10.1101/2023.12.16.572007 — Posted: 2023-12-17
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation
Bertran, M. T., Walmsley, R., Cummings, T. F. M., Aramburu, I., Benton, D. J., Assalaarachchi, J., Chasampalioti, M., Swanton, T., Joshi, D., Federico, S., Okkenhaug, H., Yu, L., Oxley, D., Walker, S., Papayannopoulos, V., Suga, H., Christophorou, M. A., Walport, L. J.
10.1101/2023.12.12.571217 — Posted: 2023-12-12
Brain-wide activity-identity mapping of neural networks associated with prosocial motivation in rats
Ruzal, K., Trachtenberg, E., Kantor, B., Flumin, H., Roemer, A., Crespo, A., Kohl, J., Ben-Ami Bartal, I.
10.1101/2023.12.10.570980 — Posted: 2023-12-11
The Legionella collagen-like protein employs a unique binding mechanism for the recognition of host glycosaminoglycans
Rehman, S., Antonovic, A., McIntire, I., Zheng, H., Cleaver, L., Adams, C., Portlock, T., Richardson, K., Shaw, R., Oregioni, A., Mastroianni, G., Whittaker, S., Kelly, G., Fornili, A., Cianciotto, N., Garnett, J.
10.1101/2023.12.10.570962 — Posted: 2023-12-10
Antigenic and genetic diversity of H1 and H3 influenza A viruses in swine in Brazil
Lopes, S., Anderson, T. K., Schaefer, R., Tochetto, C., Gava, D., Cantao, M. E., Ciacci-Zanella, J. R., Vincent Baker, A. L., Lewis, N. S.
10.1101/2023.12.01.569635 — Posted: 2023-12-02

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