Channel:  Francis Crick Institute

1,267 Articles

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Type I interferons induced upon respiratory viral infection impair lung metastatic initiation
Farias, A., Bridgeman, V., Rodrigues, F., Owen, A., Ruhland, S., Ferreira, R., Mack, M., Malanchi, I., Johansson, C.
10.1101/2024.12.23.630113 — Posted: 2024-12-23
Modelling co-development between somites and neural tube with human Trunk-like Structures (hTLS)
Makwana, K., Tilley, L., Chakravarty, P., Thompson, J., Baillie-Benson, P., Rodriguez-Polo, I., Moris, N.
10.1101/2024.12.16.628661 — Posted: 2024-12-17
Bounded optimality of time investments in rats, mice, and humans
Ott, T., Bosc, M., Sanders, J. I., Masset, P., Kepecs, A.
10.1101/2024.12.09.627552 — Posted: 2024-12-15
Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and cone function in retinal organoids
Mejecase, C., Zhou, Y., Owen, N., Soro-Barrio, P., Cheloni, R., Nair, N., Sarkar, H., Toualbi, L., Moosajee, M.
10.1101/2024.12.11.627489 — Posted: 2024-12-15
Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes
Watt, F. M., Zijl, S., Hiratsuka, T., Mobasseri, A., Ebrahimkutty, M., Boermel, M., Garcia-Manyes, S.
10.1101/2024.12.09.627463 — Posted: 2024-12-09
Epigenetic investigation of multifocal small intestinal neuroendocrine tumours reveals accelerated ageing of tumours and epigenetic alteration of metabolic genes
Webster, A. P., Makinen, N., Mensah, N., Castignani, C., Larose Cadieux, E., Shivdasani, R., Singh, P., Vaikkinen, H., Dhami, P., Ecker, S., Brown, M., Rimmer, B., Henderson, S., Herrero, J., Suderman, M., Yousefi, P. D., Beck, S., Van Loo, P., Nakakura, E., Thirlwell, C.
10.1101/2024.12.02.626017 — Posted: 2024-12-05
The essential host genome for Cryptosporidium intracellular survival exposes metabolic dependencies that can be leveraged for treatment
Marzook, N. B., Song, O.-R., Baumgärtel, L., Bernitz, N., Mkandawire, T. T., Watson, L. C., Nunes, V., Warchal, S., MacRae, J. I., Howell, M., Sateriale, A.
10.1101/2024.12.04.626561 — Posted: 2024-12-05
HIFalpha isoform specific activities drive cell-type specificity of VHL-associated oncogenesis
Lima, J. D. C. C., Hooker, M., Li, R., Barros, A. B., Masson, N., Pugh, C. W., Mole, D. R., Adam, J., Ratcliffe, P. J., Kurlekar, S.
10.1101/2024.11.28.625663 — Posted: 2024-12-03
Cross-tissue isoform switches by human transcription factors suggest a widespread regulatory mechanism
Sidorov, S., Pal, K., Lenhard, B., Luscombe, N. M.
10.1101/2024.11.28.625692 — Posted: 2024-11-29
Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition.
Krishnan, S., Lima, A., Low, Y. T., Montero, S. P., Tan, S., Gregorio, A. D., Barreto, A. P., Bowling, S., Vousden, K., Rodriguez, T. A.
10.1101/2024.11.28.625863 — Posted: 2024-11-28

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