Channel:  The Howard Hughes Medical Institute (HHMI)

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Structure and DNA bridging activity of the essential Rec114-Mei4 trimer interface
Liu, K., Grasso, E. M., Pu, S., Eliezer, D., Liu, S., Keeney, S.
10.1101/2023.01.18.524603 — Posted: 2023-01-18
Experimental Tests of the Virtual Circular Genome Model for Non-enzymatic RNA Replication
Ding, D., Zhou, L., Mittal, S., Szostak, J. W.
10.1101/2023.01.16.524303 — Posted: 2023-01-18
Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome
Feng, X., Cui, X., Zhang, L.-S., Ye, C., Wang, P., Zhong, Y., Zheng, Z., He, C.
10.1101/2023.01.16.524325 — Posted: 2023-01-17
Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain
Ganz, J., Luquette, L. J., Bizzotto, S., Bohrson, C., Jin, H., Miller, M. B., Zhou, Z., Galor, A., Park, P. J., Walsh, C. A.
10.1101/2023.01.14.523958 — Posted: 2023-01-14
A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies
Martin Alonso, C., Tabrizi, S., Xiong, K., Blewett, T., Patel, S., An, Z., Sridhar, S., Bekdemir, A., Shea, D., Amini, A. P., Wang, S.-T., Kirkpatrick, J., Rhoades, J., Golub, T., Love, J. C., Adalsteinsson, V., Bhatia, S.
10.1101/2023.01.13.524003 — Posted: 2023-01-14
An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies
Tabrizi, S., Martin-Alonso, C., Xiong, K., Blewett, T., Sridhar, S., An, Z., Patel, S., Rodriguez-Aponte, S. A., Naranjo, C. A., Wang, S.-T., Shea, D., Golub, T., Bhatia, S., Adalsteinsson, V., Love, J. C.
10.1101/2023.01.13.523947 — Posted: 2023-01-14
Transplantation-based screen uncovers inducers of muscle progenitor cell engraftment across vertebrate species
Tavakoli, S., Garcia, V., Gahwiler, E., Adatto, I., Rangan, A., Messemer, K., Ashrafi Kakhki, S., Yang, S., Chan, V., Manning, M., Fotowat, H., Wagers, A., Zon, L.
10.1101/2023.01.13.523942 — Posted: 2023-01-14
Design of amyloidogenic peptide traps
Sahtoe, D. D., Andrzejewska, E. A., Han, H. L., Rennella, E., Schneider, M. M., Meisl, G., Ahlrichs, M., Decarreau, J., Nguyen, H., Kang, A., Levine, P. M., Lamb, M., Li, X., Bera, A. K., Kay, L. E., Knowles, T., Baker, D.
10.1101/2023.01.13.523785 — Posted: 2023-01-13
Bacterial meningitis in the early postnatal mouse studied at single-cell resolution
Wang, J., Rattner, A., Nathans, J.
10.1101/2023.01.11.523597 — Posted: 2023-01-11
The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation.
Li, Z., Wang, M., Zhong, Z., Gallego-Bartolome, J., Feng, S., Jami-Alahmadi, Y., Wang, X., Wohlschlegel, J., Bischof, S., Long, J. A., Jacobsen, S. E.
10.1101/2023.01.10.523455 — Posted: 2023-01-10

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