Channel: The Howard Hughes Medical Institute (HHMI)

2,180 Articles

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Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses

Boys, I. N., Johnson, A. G., Quinlan, M., Kranzusch, P. J., Elde, N. C.

10.1101/2023.02.26.529821 — Posted: 2023-04-03

Matrin3 mediates differentiation through stabilizing chromatin accessibility and chromatin loop-domain interactions, and YY1 mediated enhancer-promoter interactions

Orkin, S. H., Liu, T., Zhu, Q., Kai, Y., Bingham, T., Cha, H., Mehta, S., Schlaeger, T. M., Yuan, G.-C.

10.1101/2023.03.30.534959 — Posted: 2023-03-31

APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1

Ikeda, T., Shimizu, R., Nasser, H., Carpenter, M. A., Cheng, A. Z., Brown, W. L., Sauter, D., Harris, R. S.

10.1101/2023.03.28.534666 — Posted: 2023-03-30

Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities

Garg, V., Yang, Y., Nowotschin, S., Setty, M., Kuo, Y.-Y., Sharma, R., Polyzos, A., Salataj, E., Murphy, D., Jang, A., Pe'er, D., Apostolou, E., Hadjantonakis, A.-K.

10.1101/2023.03.28.534648 — Posted: 2023-03-29

Genetics of Latin American Diversity (GLAD) Project: insights into population genetics and association studies in recently admixed groups in the Americas

Borda, V., Loesch, D. P., Guo, B., Laboulaye, R., Veliz-Otani, D., French-Kwawu, J. N., Peixoto Leal, T., Gogarten, S. M., Ikpe, S., Gouveia, M. H., Mendes, M., Abecasis, G. R., Alvim, I., Arboleda-Bustos, C. E., Arboleda, G., Arboleda, H., Barreto, M. L., Barwick, L., Bezzera, M. A., Blangero, J., Borges, V., Caceres, O., Cai, J., Chana-Cuevas, P., Chen, Z., Custer, B., Dean, M., Dinardo, C., Domingos, I., Duggirala, R., Dieguez, E., Fernandez, W., Ferraz, H. B., Gilliland, F. D., Guio, H., Horta, B., Curran, J. E., Johnsen, J. M., Kaplan, R. C., Kelly, S., Kenny, E. E., Konkle, B. A., Kooper

10.1101/2023.01.07.522490 — Posted: 2023-03-29

Design and implementation of suspended drop crystallization

Gonen, T., Gillman, C., Martynowycz, M., Nicolas, W. J.

10.1101/2023.03.28.534639 — Posted: 2023-03-28

Intrinsic protein disorder is insufficient to drive subnuclear clustering in embryonic transcription factors

Hannon, C. E., Eisen, M. B.

10.1101/2023.03.27.534457 — Posted: 2023-03-28

SLAPSHOT reveals rapid dynamics of extracellularly exposed proteome in response to calcium-activated plasma membrane phospholipid scrambling

Tuomivaara, S. T., Teo, C. F., Jan, Y. N., Jan, L. Y., Wiita, A. P.

10.1101/2023.03.26.534250 — Posted: 2023-03-26

Split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80

Ewen-Campen, B., Luan, H., Xu, J., Singh, R., Joshi, N., Thakkar, T., Berger, B., White, B., Perrimon, N.