Channel:  The Howard Hughes Medical Institute (HHMI)

2,398 Articles

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Expansion of human centromeric arrays in cells undergoing break-induced replication
Showman, S., Talbert, P. B., Xu, Y., Adeyemi, R. O., Henikoff, S.
10.1101/2023.11.11.566714 — Posted: 2023-11-15
Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery
Yang, J. L., Yamada-Hunter, S. A., Labanieh, L., Sotillo, E., Cheah, J. S., Roberts, D. S., Mackall, C., Ting, A. Y., Bertozzi, C.
10.1101/2023.11.14.567117 — Posted: 2023-11-15
Cell type-specific effects of age and sex on human cortical neurons
Chien, J.-F., Liu, H., Wang, B.-A., Luo, C., Bartlett, A., Castanon, R., Johnson, N. D., Nery, J. R., Osteen, J., Li, J., Altshul, J., Kenworthy, M., Valadon, C., Liem, M., Claffey, N., O'Connor, C., Seeker, L. A., Ecker, J. R., Behrens, M. M., Mukamel, E. A.
10.1101/2023.11.11.566717 — Posted: 2023-11-15
Engineering self-deliverable ribonucleoproteins for genome editing in the brain
Chen, K., Stahl, E. C., Kang, M. H., Xu, B., Allen, R., Trinidad, M., Doudna, J. A.
10.1101/2023.11.15.567251 — Posted: 2023-11-15
Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP
Chen, K., Han, H., Zhao, S., Xu, B., Yin, B., Trinidad, M., Burgstone, B. W., Murthy, N., Doudna, J. A.
10.1101/2023.11.15.566339 — Posted: 2023-11-15
Structural basis for VLDLR recognition by eastern equine encephalitis virus
Yang, P., Li, W., Fan, X., Pan, J., Mann, C. J., Varnum, H., Clark, L. E., Clark, S. A., Coscia, A., Smith, K. N., Brusic, V., Abraham, J.
10.1101/2023.11.14.567065 — Posted: 2023-11-14
Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome
Chan, J. C., Alenina, N., Cunningham, A. M., Ramakrishnan, A., Shen, L., Bader, M., Maze, I.
10.1101/2023.11.14.567020 — Posted: 2023-11-14
Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
Dadonaite, B., Brown, J., McMahon, T. E., Farrell, A. G., Asarnow, D., Stewart, C., Logue, J., Murrell, B., Chu, H. Y., Veesler, D., Bloom, J. D.
10.1101/2023.11.13.566961 — Posted: 2023-11-14
Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment
Daugird, T. A., Shi, Y., Holland, K. L., Rostamian, H., Liu, Z., Lavis, L. D., Rodriguez, J., Strahl, B. D., Legant, W. R.
10.1101/2023.11.09.566470 — Posted: 2023-11-13
Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells
Iascone, D. M., Zhang, X., Bafford, P., Mesaros, C., Sela, Y., Hofbauer, S., Zhang, S. L., Cook, K., Pivarshev, P., Stanger, B., Anderson, S. A., Dang, C. V., Sehgal, A.
10.1101/2023.11.08.566310 — Posted: 2023-11-13

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