Channel:  The Howard Hughes Medical Institute (HHMI)

2,105 Articles

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Persistence of backtracking by human RNA polymerase II
Yang, K. B., Rasouly, A., Epshtein, V., Martinez, C., Nguyen, T., Shamovsky, I., Nudler, E.
10.1101/2023.12.13.571520 — Posted: 2023-12-19
Cell type specific enrichment of somatic aneuploidy in the mammalian brain
Mukamel, E. A., Liu, H., Behrens, M. M., Ecker, J. R.
10.1101/2023.12.18.572285 — Posted: 2023-12-19
The membrane curvature inducing REEP1 proteins generate a novel ER-derived vesicular compartment
Shibata, Y., Mazur, E. E., Pan, B., Hernandez, S. V., Zhang, J., Rapoport, T. A.
10.1101/2023.12.19.572386 — Posted: 2023-12-19
VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
Ugur, B., Schueder, F., Shin, J., Hanna, M. G., Wu, Y., Leonzino, M., Su, M., McAdow, A. R., Wilson, C. A., Postlethwait, J., Solnica-Krezel, L., Bewersdorf, J., De Camilli, P.
10.1101/2023.12.18.572081 — Posted: 2023-12-18
Imaging the voltage of neurons distributed across entire brains of larval zebrafish
Wang, Z., Zhang, J., Symvoulidis, P., Guo, W., Zhang, L., Wilson, M. A., Boyden, E. S.
10.1101/2023.12.15.571964 — Posted: 2023-12-16
Connectivity underlying motor cortex activity during naturalistic goal-directed behavior
Finkelstein, A., Daie, K., Rozsa, M., Darshan, R., Svoboda, K.
10.1101/2023.11.25.568673 — Posted: 2023-12-15
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Eggers, A. R., Chen, K., Soczek, K. M., Tuck, O. T., Doherty, E. E., Thornton, B. W., Xu, B., Trinidad, M. I., Doudna, J. A.
10.1101/2023.12.14.571777 — Posted: 2023-12-15
Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
Martin, A., Lopez-Alfonzo, E. M., Saurabh, A., Zarafshan, S., Presse, S.
10.1101/2023.12.14.571752 — Posted: 2023-12-15
A translation-independent directed evolution strategy to engineer aminoacyl-tRNA synthetases
Soni, C., Prywes, N., Hall, M., Savage, D. F., Schepartz, A., Chatterjee, A.
10.1101/2023.12.13.571473 — Posted: 2023-12-14
The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation
Mehta, N., Mondal, S., Watson, E. T., Cui, Q., Chapman, E. R.
10.1101/2023.08.11.551903 — Posted: 2023-12-13

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