COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,031 Articles (22,627 medRxiv, 8,404 bioRxiv)

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Modeling the Anticipated Public Health Benefits of the Next-Generation COVID-19 mRNA-1283 vaccine: An Interim U.S. Population-Level Impact Assessment
Fust, K., Kohli, M., Joshi, K., Cartier, S., Lee, A., Van de Velde, N., Weinstein, M. C., Beck, E.
10.1101/2025.09.26.25336704 — Posted: 2025-09-28
Pre-existing and new users of psychotherapy and pharmacotherapy for common mental disorders during the COVID-19 pandemic: a population-based study
Pouquet, M., Davisse-Paturet, C., Vuillermoz, C., Debin, M., Kengue, C., Turbelin, C., Blanchon, T., Steichen, O., Tournier, M., Younes, N.
10.1101/2025.09.24.25336577 — Posted: 2025-09-26
Intensive care unit and hospital mortality for non-COVID critically ill patients before, and during the COVID-19 pandemic in Alberta hospitals: retrospective, observational cohort study
Lau, V. I., Hammal, F., Sligl, W., Karvellas, C., Kutsogiannis, D. J., Zampieri, F., Wilcox, M. E., Fiest, K., Niven, D., Stelfox, H. T., Zuege, D., Parhar, K. K. S., Bagshaw, S. M., Rewa, O. S.
10.1101/2025.09.25.25336571 — Posted: 2025-09-26
ISG15 Differentially Modulates Clade Ib and II MPXV Infection in MEF cells
McGrail, J. P., Campana Gomez, I., Tuhkala, A., Keskitalo, S. E., Varjosalo, M., Garcia-Sastre, A., Palacios, G. F., Sanchez-Seco, M. P., Guerra, S.
10.1101/2025.09.26.678780 — Posted: 2025-09-26
A Comparative Nanomechanical Study of Antibody and Nanobody Binding to SARS-CoV-2 Variants
Cofas-Vargas, L. F., Olivos-Ramirez, G. E., Marrink, S.-J., Poma, A. B.
10.1101/2025.09.26.672567 — Posted: 2025-09-26
Whole-genome DNA methylation profiling in COVID-19 positive patients reveals alterations in pathways linked to neurological dysfunction
Zameer, S., Anis, E., Sha, Q., Escobar Galvis, M. L., Khan, S., Steiner, J. A., Milciute, M., Kerseviciute, I., Gabrielaite, M., Gordevicius, J., Pospisilik, A., Saiyed, N., Graham, S. F., Brundin, P., Brundin, L.
10.1101/2025.09.25.678349 — Posted: 2025-09-25
DYNAMICS OF RHINOVIRUS SARS-COV-2 COINFECTIONS AND SUPERINFECTIONS IN HUMAN AIRWAY CULTURES REVEAL TYPE-DEPENDENT VIRAL INTERFERENCE
Volle, R.
10.1101/2025.09.24.678304 — Posted: 2025-09-25
A Systematic Review of Spatial Epidemiological Modeling Approaches Applied During the COVID-19 Pandemic
Oshinubi, K., Chen, Y., Doerry, E., Gel, E. S., Hepp, C. M., Lant, T. M., Mehrotra, S., Sabo, S., Mihaljevic, J. R.
10.1101/2025.09.24.25336493 — Posted: 2025-09-25
Late treatment initiation leads to reduced antiviral potency
Liu, X., Franco, E. J., Avedissian, S. N., Hanrahan, K. C., Guedj, J., van Hasselt, J. G. C., Brown, A. N., Martson, A.-G.
10.1101/2025.09.24.678199 — Posted: 2025-09-25
SARS-CoV-2 ORF7a Drives Mitochondrial Dysfunction via PDK4 Activation and Complex I Inhibition
Fernandez-Rodriguez, R., Soto-Jimenez, C. M., Acin-Perez, R., de Lucas-Rius, A., Sanchez-Mendoza, L. M., Lopez-Ayllon, B. D., Villalba, J. M., Enriquez, J. A., Montoya, M., Garrido, J. J., Garcia-Garcia, T.
10.1101/2025.09.25.678549 — Posted: 2025-09-25

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).