COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,024 Articles (22,627 medRxiv, 8,397 bioRxiv)

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Immune Cell Dysfunction of SARS-CoV-2: Mathematical Modeling of the Within-Host Immune Dynamics
Ngoun, P., Alvarez, N., Awad, A., Ryu, H.
10.1101/2025.10.03.680253 — Posted: 2025-10-03
Discovery of rare antigen-specific TCRs via replicate profiling
Egorov, E. S., Kriukova, V. V., Shagina, I. A., Sharonov, G. V., Lupyr, K. R., Staroverov, D. B., Lukyanov, D. K., Salnikova, M. A., Nikolaev, R. N., Shelikhova, L., Lopukhova, G. A., Altunina, A. M., Turchaniniova, M. A., Britanova, O. V., Bryushkova, E. A., Maschan, M. A., Martinez Carrera, L. A., Jelveh, N., Bisdorf, K., Matzke, S. K., Khorkova, S., Bosio, A., Hardt, O., Franke, A., Chudakov, D., Serebrovskaya, E. O.
10.1101/2025.09.30.675572 — Posted: 2025-10-03
Cathepsin K as a Key SARS-CoV-2 Cell Entry Protease and Dual-Inhibition Target
Tabatabaei Dakhili, S. Y., Saha, D., Panwar, P., Mar, E., Hinse, O., Chen, Y. S., Fraser, B. J., Arrowsmith, C., Niikura, M., Van Petegem, F., Bromme, D.
10.1101/2025.10.03.680348 — Posted: 2025-10-03
Neanderthal Introgressed COVID-19 Risk Locus 3p21.31 Under Positive Selection in East Asia via LZTFL1-Driven Ciliary Changes
Pandey, R. K., Desai, S., Chaubey, G.
10.1101/2025.10.01.679818 — Posted: 2025-10-03
PM2.5 Exposure Facilitates SARS-CoV-2 Infection through ACE2/TMPRSS2 Regulation and Suppression of Anti-Viral Response
Rajabi, H., Kayalar, O., Esken, G., Can, F., Bayram, H.
10.1101/2025.10.02.679237 — Posted: 2025-10-03
Computational Analysis of Silent Mutation Effects on SARS-CoV-2 RNA-Host RNA-Binding Protein Interactome
Bello, A. J., Chukwudozie, O. S., Oladapo, O. B., Omotuyi, A. O., Nzoniwu, N. A., Amusa, O. D., Ottu, B. O., Okeke, U., Adewole, A. O., Akinnusi, O. O., Kade, A. E., Minari, J. B., Okpuzor, J., Folarin, O., Shittu, M. O.
10.1101/2025.09.22.677528 — Posted: 2025-10-03
IgG4 Neutralization and Sustained Total IgG Fc-Effector Functions Following Repeated SARS-CoV-2 mRNA Vaccination
Kaplonek, P., Bertera, H., Lee, D. W., Cizmeci, D., Yu, W.-H., Wu, K., Chalkias, S., Wahid, R., Edwards, D. K., Alter, G., Henry, C.
10.1101/2025.09.30.25336755 — Posted: 2025-10-02
Dynamical survival analysis for epidemic modeling under partial observability: A case study of COVID-19 in Kenya
KAGUNDA, J. W., Gothard, A., Rempala, G., Choi, B.
10.1101/2025.09.30.25337023 — Posted: 2025-10-02
Quantifying SARS-CoV-2 Omicron variant spread and the impact of non-pharmaceutical interventions in Newfoundland and Labrador, Canada
Anokye, F., Li, M. W., Walker, S., Hurford, A.
10.1101/2025.09.26.25336738 — Posted: 2025-10-02
Leveraging Multimodal Large Language Models to Extract Mechanistic Insights from Biomedical Visuals: A Case Study on COVID-19 and Neurodegenerative Diseases
Popova, E., Jacobs, M., Hofmann-Apitius, M., Babaiha, N. S.
10.1101/2025.10.01.679928 — Posted: 2025-10-02

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).