COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,249 Articles (22,733 medRxiv, 8,516 bioRxiv)

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The effect of SARS-CoV-2 testing on healthcare seeking behaviour at primary care level: implications for COVID-19 vaccine effectiveness estimates in test-negative design studies.
van Hagen, C. C. E., Vos, E. R. A., Laniece Delaunay, C., de Melker, H. E., Kissling, E., Knol, M. J.
10.1101/2025.03.31.25324928 — Posted: 2025-04-01
Effectiveness of COVID-19 vaccine booster doses in adults aged 50 years and over during the Omicron period in Victoria, Australia
Szanyi, J., Yang, Y., Zeng, J., Clarke, C., Buttery, A. K., Blakely, T.
10.1101/2025.03.31.25324986 — Posted: 2025-04-01
The development and usability testing of six arts-based knowledge translation tools for parents about COVID-19
Scott, S. D., Elliott, S. A., Reid, K., Knisley, L., Hartling, L.
10.1101/2025.03.31.25324968 — Posted: 2025-04-01
Ketamine inhibition of SARS-CoV-2 replication in astrocytes is associated with COVID-19 disease severity in a variant-dependent manner
Furlani, B., Potokar, M., Korva, M., Resman Rus, K., Pozvek, P., Zorec, T. M., Vrsnik, J., Pirnat, S., Tavcar Verdev, P., Smolic, T., Horvat, A., Radinovic, K., Graselli Kmet, N., Avsic-Zupanc, T., Vardjan, N., Stenovec, M., Jereb, M., Jorgacevski, J., Zorec, R.
10.1101/2025.03.29.646083 — Posted: 2025-04-01
Modeling viral and bacterial infections in human lung organotypic systems reveals strain specific host responses
Faria Fonseca, B., Wong-Ng, J., Connor, M., Mary, H., Kim, M. H., Yim, R., BONDET, V., Michel, V., Strick Marchand, H., Di Santo, J. P., Duffy, D., Hamon, M. A., Sauvonnet, N., Chakrabarti, L. A., Gobaa, S.
10.1101/2025.03.31.644992 — Posted: 2025-04-01
A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding
Hess, S., Campos-Alonso, M., Brand, M., Lauw, S., Lindenmann, U., Goebel, K., Geurink, P. P., Fritz, G., Riedl, R., Knobeloch, K.-P.
10.1101/2025.03.30.646166 — Posted: 2025-04-01
Divalent cations govern the activity of coronavirus nsp15
Wang, X., Li, J., Liu, Z., Wang, L., Zhu, B.
10.1101/2025.03.29.646087 — Posted: 2025-03-31
Functional and structural characterization of a combination of pan-sarbecovirus antibodies with potent antiviral activity
Marden, G. C., Schmitt, K. P., Zimmerman, M. I., Ramos, A. H., Menzenski, M. Z., Sharma, G., Li, H., Carlin, E., Jecrois, A., Morales-Perez, C. L., Palovcak, E., Garlick, J. D., Hannigan, B., Russell, P., Federman, R. S., Leung, A., Vargas, N. L., Shaban, N. M., Vaidya, V., Towler, H., Joh, N. H., Lord, D. M., Tao, J., Costello, Z., Frappier, V., Hopson, K., Pegu, A., Koh, G. C. K. W., Van Epps, H., Root, A., Grigoryan, G., Hazuda, D., Borriello, F.
10.1101/2025.03.30.646023 — Posted: 2025-03-31
The CCR2 inflammatory pathway is a target for improving severe disease and pulmonary inflammation in experimental COVID-19
Kazungu, Y., Hegde, S., Sharma, P., Marriott, A., Steven, A., Reine, J., Dagley, J. L., Mack, M., Stewart, J. P., Turner, J. D.
10.1101/2025.03.28.645941 — Posted: 2025-03-31
Gut barrier integrity biomarkers are associated with increased inflammation and predict disease status in hospitalized COVID-19 patients
Basting, C. M., Schroeder, T., Ferbas, K., Shields-Cutler, R., Tobin, N., Velez, A., Swanson, E., Broedlow, C. A., Langat, R., Schifanella, L., Bramante, C. T., Aldrovandi, G. M., Rimoin, A., Yang, O. O., Fulcher, J. A., Klatt, N. R.
10.1101/2025.03.28.645914 — Posted: 2025-03-31

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).