COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,387 Articles (22,816 medRxiv, 8,571 bioRxiv)

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Multi-step antibody class switching in a primary human response is restricted after IGHG2 and dependent on B cell maturation stage.
Garcia, G. M., Ng, J. C., Stewart, A. T., Sinclair, E., Blair, P., Kateregga, D., Gander, A., Kipling, D., Guo, D., Servius, L., Piper, C., Baig, Z., Fraternali, F., Mauri, C., Dunn-Walters, D.
10.1101/2025.05.07.652638 — Posted: 2025-05-08
No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo
Fortin, A., Huot, S., Caron, E., Laflamme, C., Pagliuzza, A., Chomont, N., Gilbert, C., Zhang, B., Kwong, P. D., Pouliot, M., Grandvaux, N.
10.1101/2025.05.08.652856 — Posted: 2025-05-08
Beyond Natural Antibodies: Scaffold-Based Generation of Novel Anti-3CLpro Nanobody Nb01
Zhan, Z., Luo, C., Xiong, J., Jiang, Y., Li, Y., Huang, F., Cai, Y., Liu, J.
10.1101/2025.05.06.652338 — Posted: 2025-05-07
Discovery of an Antiviral PROTAC Targeting the SARS-CoV-2 Main Protease Using an Allosteric Warhead
Veeck, C., Laube, L., Werner, A. D., Diederich, W., Becker, S.
10.1101/2025.05.03.652023 — Posted: 2025-05-07
Number of Austrian SARS-CoV-2 infections in the 2024/2025 season: Analysis of national wastewater data
Riedmann, U., Rauch, W., Schenk, H., Oberacher, H., Ioannidis, J., Pilz, S.
10.1101/2025.05.05.25327005 — Posted: 2025-05-06
Parametric Survival Analysis of Long COVID Among Hospitalized Patients in Zambia: A Retrospective Cohort Study on the Time to Symptoms Resolving
Malambo, W., Sampa-Kawana, M., Chanda, D., Folowshi, S., Hines, J. Z., Kaonga, P.
10.1101/2025.05.05.25327037 — Posted: 2025-05-06
Opioid prescribing to people on orthopaedic waiting lists during the COVID-19 pandemic in England: a study using OpenSAFELY-TPP
Higgins, R., Smith, R. M., Dillingham, I., Quinlan, J., Speed, V., Curtis, H. J., Wood, C., Wiedemann, M., Jani, M., Bacon, S. C., Mehrkar, A., Goldacre, B., The OpenSAFELY Collaborative, , MacKenna, B., Schaffer, A. L.
10.1101/2025.05.06.25326436 — Posted: 2025-05-06
A Cluster of Acidic Residues in the Cytoplasmic Domain of SARS-CoV-2 Spike is Required for Virion-Incorporation and Infectivity
Stoneham, C. A., Singh, R., De Leon, A., Tafelmeyer, P., Acosta, F., Fuori, A., Anderson, M., Ramirez, P. W., Schwartzer-Sperber, H. S., Pillai, S. K., Lewinski, M. K., Guatelli, J.
10.1101/2025.05.04.652125 — Posted: 2025-05-06
Ethnic inequalities in compulsory psychiatric hospital detentions during UK COVID-19 'lockdowns': A Regression Discontinuity Design in time study
Hildersley, R. R., Oswald, T., Bakolis, I., Becares, L., Dregan, A., Dyer, J., Hotopf, M., Ocloo, J., Stewart, R., Das-Munshi, J.
10.1101/2025.05.02.25326888 — Posted: 2025-05-06
Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest
Charlton, B. T., Slaghekke, A., Appelman, B., Eggelbusch, M., Huijts, J. Y., Noort, W., Hendrickse, P. W., Bloemers, F. W., Posthuma, J. J., van Amstel, P., Goulding, R. P., Degens, H., Jaspers, R. T., van Vugt, M., Wust, R.
10.1101/2025.05.02.25326885 — Posted: 2025-05-06

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).