COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,695 Articles (22,913 medRxiv, 8,782 bioRxiv)

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Temporal Dynamics of Antigen-Specific T Cell Expansion in Primary SARS-CoV-2 Infection
Pyo, A. G. T., Chan, A., Rosenheim, J., Thakker, C., Bell, L., Nageswaran, G., Byrne, S., Killingley, B., Scobie, D., Kalinova, M., Boyers, A., Catchpole, A., Mann, A., Lindeboom, R. G. H., Nikolic, M. Z., Teichmann, S., Wagstaffe, H., Noursadeghi, M., Chiu, C., Callan, C., Mayer, A., Wingreen, N. S., Chain, B.
10.1101/2025.11.04.686558 — Posted: 2025-11-05
Natural History of Self-reported Symptoms Following SARS-CoV-2 Infection: A Target Trial Emulation in a Prospective Community-Based Cohort
Shen, Y., Shahn, Z., Robertson, M., Gebo, K., Nash, D.
10.1101/2025.11.01.25339316 — Posted: 2025-11-04
Re-evaluating the effect of SARS-CoV-2 mRNA vaccination on clinical outcomes in patients treated with immune checkpoint inhibitors
Dumas, E., Gougis, P., Gasparollo, L., Spano, J.-P., Stensrud, M. J.
10.1101/2025.11.03.25339367 — Posted: 2025-11-04
Neuroimmune pleiotropy links COVID-19 outcomes to brain structural and functional imaging-derived phenotypes
Chen, Q., He, J., Cabrera Mendoza, B., Xu, Z., Qiu, D., Polimanti, R.
10.1101/2025.11.03.25339411 — Posted: 2025-11-04
Long COVID Longitudinal Symptoms Burden Clusters Within A National Community-Based Cohort
Shen, Y., Shahn, Z., Robertson, M., Gebo, K., Nash, D.
10.1101/2025.11.01.25339283 — Posted: 2025-11-04
Persistent Classical and Atypical Memory B Cells Underlie Heterogeneous Vaccine Responses in Ocrelizumab-Treated Multiple Sclerosis
Curtin, R., Velmurugu, Y., Dibba, F., Hao, Y., Sreenivasaiah, C., Khodadadi-Jamayran, A., Nyovanie, S. T., Kim, A., Samanovic-Golden, M., Mulligan, M. J., Priest, J., Cabatingan, M., Winger, R., Patskovsky, Y., Kister, I., Silverman, G. J., Krogsgaard, M.
10.1101/2025.11.03.686372 — Posted: 2025-11-04
The coronavirus envelope is conserved, contains bioactive lipids needed for replication, and is modulated in response to host inflammation
Tyrrell, V., Zaragkoulias, A., Powell, W., Elfar, M., Grossoni, V., Monaco, F., Protty, M., Stenhouse, E., Heyman, J., Costa, D., Roche, L., Lynch, C.-A. B., Ghazal, P., Jones, S. A., Lambeau, G. A., Benatzy, Y., Kandler, J., Bojkova, D., Snodgrass, R., Brune, B., Thomas, D., Stanton, R., O'Donnell, V.
10.1101/2025.11.03.686211 — Posted: 2025-11-03
Tracking the opening of spike crowns on the surface of coronaviruses
Wu, D.
10.1101/2025.11.02.686173 — Posted: 2025-11-03
Caspase-11 Mediated Hyperinflammation Impairs CD8⁺ T Cell Immunity and Viral Clearance in Severe SARS-CoV-2 Infection
ELTOBGY, M., Shamseldin, M., Whitham, O., Amer, H., Atkinson, J., Badr, A., Hall, J., Omran, J., Gupta, G., Hassan, Y., Abdelaleem, R., Perez, R., Faber, S., Pietrzak, M., Webb, A., Zhang, X., Kenney, A., Bissel, D., Estfanous, S., Daily, K., Mcnamara, A., KC, M., Peeples, M., Hemann, E., Nimjee, S., Cormet-Boyaka, E., Li, J., Boyaka, P., Yount, J., Segal, B., Dubey, P., Amer, A.
10.1101/2025.11.01.684729 — Posted: 2025-11-03
Neutral Frustration Landscape Architecture of SARS-CoV-2 Spike -Antibody Interfaces Shapes Immune Evasion Mechanisms for Ultrapotent Neutralizing Antibodies and Determines Pathways of Viral Adaptation: Insights from Integrative Computational Approach
Alshahrani, M., Parikh, V., Foley, B., Verkhivker, G.
10.1101/2025.10.31.685956 — Posted: 2025-11-03

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).