COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,620 Articles (22,913 medRxiv, 8,707 bioRxiv)

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Validation and Comparison of a Modified CDC Assay with two Commercially Available Assays for the Detection of SARS-CoV-2 in Respiratory Specimen
Lima, A., Healer, V., Vendrone, E., Silbert, S.
10.1101/2020.06.29.179192 — Posted: 2020-06-30
SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 elicits immunogenicity in baboons and protection in mice
Tian, J.-H., Patel, N., Haupt, R., Zhou, H., Weston, S., Hammond, H., Lague, J., Portnoff, A. D., Norton, J., Guebre-Xabier, M., Zhou, B., Jacobson, K., Maciejewski, S., Khatoon, R., Wisniewska, M., Mottitt, W., Kluepfel-Stahl, S., Ekechukwu, B., Papin, J., Boddapati, S., Wong, C. J., Piedra, P. A., Frieman, M. B., Massare, M. J., Fries, L., Lovgren Bengtsson, K., Stertman, L., Ellingsworth, L. R., Glenn, G., Smith, G.
10.1101/2020.06.29.178509 — Posted: 2020-06-30 Discussion: Onsite
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies
Acharya, P., Williams, W., Henderson, R., Janowska, K., Manne, K., Parks, R., Deyton, M., Sprenz, J., Stalls, V., Kopp, M., Mansouri, K., Edwards, R. J., Meyerhoff, R., Oguin, T., Sempowski, G., Saunders, K. O., Haynes, B. F.
10.1101/2020.06.30.178897 — Posted: 2020-06-30
Genetic variants in TMPRSS2 and Structure of SARS-CoV-2 spike glycoprotein and TMPRSS2 complex
Vishnubhotla, R., Vankadari, N., Ketavarapu, V., Amanchy, R., Avanthi, S., Bale, G., Nageshwar Reddy, D., Sasikala, M.
10.1101/2020.06.30.179663 — Posted: 2020-06-30 Discussion: Onsite
Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
Mou, H., Quinlan, B., Peng, H., Guo, Y., Peng, S., Zhang, L., Davis-Gardner, M., Gardner, M., Voo, Z. X., Bailey, C. C., Alpert, M., Rader, C., Choe, H., Farzan, M.
10.1101/2020.06.29.178459 — Posted: 2020-06-30
Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs
Ren, L., Wu, C., Guo, L., Yao, J., Wang, C., Xiao, Y., Pisco, A. O., Wu, Z., Lei, X., Liu, Y., Shi, L., Han, L., Zhang, H., Xiao, X., Zhong, J., Wu, H., Li, M., Quake, S. R., Huang, Y., Wang, J., wang, j.
10.1101/2020.06.30.175778 — Posted: 2020-06-30 Discussion: Onsite | Offsite
A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection
Herrmann, A., Maruyama, J., Yue, C., Lahtz, C., Zhou, H., Kerwin, L., Guo, W., Zhang, Y., Soo Hoo, W., Yei, S., Kwon, S., Fu, Y., Johnson, S., Ledesma, A., Zhuang, Y., Zhuang, Y., Yei, E., Adamus, T., Praessler, S., Ji, H.
10.1101/2020.06.29.178616 — Posted: 2020-06-30 Discussion: Offsite
Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent
Hahn, G., Cho, M. H., Weiss, S. T., Silverman, E. K., Lange, C.
10.1101/2020.06.22.165936 — Posted: 2020-06-30 Discussion: Onsite
A retrospective study evaluating efficacy and safety of compassionate use of tocilizumab in 13 patients with severe-to-critically ill COVID-19: analysis of well-responding cases and rapidly-worsening cases after tocilizumab administration
Hashimoto, S., Kitajima, H., Arai, T., Tamura, Y., Nagai, T., Morishita, H., Matsuoka, H., Han, Y., Minamoto, S., Hirashima, T., Yamada, T., Kashiwa, Y., Kameda, M., Yamaguchi, S., Uno, K., Nakayama, E., Shioda, T., Yoshizaki, K., Kang, S., Kishimoto, T., Tanaka, T.
10.1101/2020.06.24.20134288 — Posted: 2020-06-30 Discussion: Offsite
Citizen Scientists Create an Exascale Computer to Combat COVID-19
Zimmerman, M. I., Porter, J. R., Ward, M. D., Singh, S., Vithani, N., Meller, A., Mallimadugula, U. L., Kuhn, C. E., Borowsky, J. H., Wiewiora, R. P., Hurley, M. F. D., Harbison, A. M., Fogarty, C. A., Coffland, J. E., Fadda, E., Voelz, V. A., Chodera, J. D., Bowman, G. R.
10.1101/2020.06.27.175430 — Posted: 2020-06-30 Discussion: Onsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).