COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,617 Articles (22,913 medRxiv, 8,704 bioRxiv)

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Anti-frameshifting ligand active against SARS coronavirus-2 is resistant to natural mutations of the frameshift-stimulatory pseudoknot
Neupane, K., Munshi, S., Zhao, M., Ritchie, D. B., Ileperuma, S. M., Woodside, M. T.
10.1101/2020.06.29.178707 — Posted: 2020-06-30
A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2
Ponce-Rojas, J. C., Costello, M. S., Proctor, D. A., Kosik, K. S., Wilson, M. Z., Arias, C., Acosta-Alvear, D.
10.1101/2020.06.29.178384 — Posted: 2020-06-30
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
Malimova, M., Sidhom, E.-H., Satyam, A., Dvela-Levitt, M., Melanson, M., Chamberlain, B. T., Alper, S. L., Santos, J., Gutierrez, J., Subramanian, A., Grinkevich, E., Bricio, E. R., Kim, C., Clark, A., Watts, A., Thompson, R., Marshall, J., Pablo, J. L., Coraor, J., Roignot, J., Vernon, K. A., Keller, K., Campbell, A., Emani, M., Racette, M., Bazua-Valenti, S., Padovano, V., Weins, A., McAdoo, S. P., Tam, F. W. K., Ronco, L., Wagner, F., Tsokos, G. C., Shaw, J. L., Greka, A.
10.1101/2020.06.30.180380 — Posted: 2020-06-30 Discussion: Offsite
Structure of the full SARS-CoV-2 RNA genome in infected cells
Lan, T. C. T., Allan, M. F., Malsick, L., Khandwala, S., Nyeo, S. S. Y., Bathe, M., Griffiths, A., Rouskin, S.
10.1101/2020.06.29.178343 — Posted: 2020-06-30 Discussion: Onsite | Offsite
SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
Huang, J., Hume, A. J., Abo, K. M., Werder, R. B., Villacorta-Martin, C., Alysandratos, K. D., Beermann, M. L., Simone-Roach, C., Olejnik, J., Suder, E., Bullitt, E., Hinds, A., Sharma, A., Bosmann, M., Wang, R., Hawkins, F., Burks, E. J., Saeed, M., Wilson, A. A., Mühlberger, E., Kotton, D. N.
10.1101/2020.06.30.175695 — Posted: 2020-06-30
Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
Xu, C., Wang, Y., Liu, C., Zhang, C., Han, W., Hong, X., Wang, Y., Hong, Q., Wang, S., Zhao, Q., Wang, Y., Yang, Y., Chen, K., Zheng, W., Kong, L., Wang, F., Zuo, Q., Huang, Z., Cong, Y.
10.1101/2020.06.30.177097 — Posted: 2020-06-30
Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V., Mishra, S., Sharma, R., Agarwal, J., Ghoshal, U., Khanna, T., Sharma, L. K., Verma, S. K., Tiwari, S.
10.1101/2020.06.30.172833 — Posted: 2020-06-30 Discussion: Onsite
Validation and Comparison of a Modified CDC Assay with two Commercially Available Assays for the Detection of SARS-CoV-2 in Respiratory Specimen
Lima, A., Healer, V., Vendrone, E., Silbert, S.
10.1101/2020.06.29.179192 — Posted: 2020-06-30
SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 elicits immunogenicity in baboons and protection in mice
Tian, J.-H., Patel, N., Haupt, R., Zhou, H., Weston, S., Hammond, H., Lague, J., Portnoff, A. D., Norton, J., Guebre-Xabier, M., Zhou, B., Jacobson, K., Maciejewski, S., Khatoon, R., Wisniewska, M., Mottitt, W., Kluepfel-Stahl, S., Ekechukwu, B., Papin, J., Boddapati, S., Wong, C. J., Piedra, P. A., Frieman, M. B., Massare, M. J., Fries, L., Lovgren Bengtsson, K., Stertman, L., Ellingsworth, L. R., Glenn, G., Smith, G.
10.1101/2020.06.29.178509 — Posted: 2020-06-30 Discussion: Onsite
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies
Acharya, P., Williams, W., Henderson, R., Janowska, K., Manne, K., Parks, R., Deyton, M., Sprenz, J., Stalls, V., Kopp, M., Mansouri, K., Edwards, R. J., Meyerhoff, R., Oguin, T., Sempowski, G., Saunders, K. O., Haynes, B. F.
10.1101/2020.06.30.178897 — Posted: 2020-06-30

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