COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,003 Articles (22,627 medRxiv, 8,376 bioRxiv)

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Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping
Schreibing, F., Hannani, M., Ticconi, F., Fewings, E., Nagai, J. S., Begemann, M., Kuppe, C., Kurth, I., Kranz, J., Frank, D., Anslinger, T. M., Ziegler, P., Kraus, T., Enczmann, J., Balz, V., Windhofer, F., Balfanz, P., Kurts, C., Marx, G., Marx, N., Dreher, M., Schneider, R. K., Saez-Rodriguez, J., Costa Filho, I. G., Kramann, R.
10.1101/2021.03.03.432690 — Posted: 2021-03-03
Maturation signatures of conventional dendritic cells in COVID-19 reflect direct viral sensing
Marongiu, L., Protti, G., Facchini, F. A., Valache, M., Mingozzi, F., Ranzani, V., Putignano, A. R., Salviati, L., Bevilacqua, V., Curti, S., Crosti, M., D'Angio, M., Bettini, L. R., Biondi, A., Nespoli, L., Tamini, N., Mancini, N., Clementi, N., Abrignani, S., Spreafico, R., Granucci, F.
10.1101/2021.03.03.433597 — Posted: 2021-03-03
Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and aberrant pattens in humans
Penrice-Randal, R., Goldswain, H., Prince, T., Randle, N., Salguero, J., Tree, J., Vamos, E., Nelson, C., ISARIC-4C Investigators, , COG-UK Consortium, , Stewart, J. P., Matthews, D. A., Carroll, M., Darby, A., Hiscox, J. A.
10.1101/2021.03.03.433753 — Posted: 2021-03-03
Recombinant protein subunit SARS-CoV-2 vaccines formulated with CoVaccine HT adjuvant induce broad, Th1 biased, humoral and cellular immune responses in mice
Lai, C.-Y., To, A., Wong, T. A. S., Lieberman, M. M., Clements, D. E., Senda, J. T., Ball, A. H., Pessaint, L., Andersen, H., Donini, O., Lehrer, A. T.
10.1101/2021.03.02.433614 — Posted: 2021-03-03
Altered Sub-Genomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections
Parker, M. D., Lindsey, B. B., Shah, D. R., Hsu, S., Keeley, A. J., Partridge, D. G., Leary, S., Cope, A., State, A., Johnson, K., Ali, N., Raghei, R., Heffer, J., Smith, N., Zhang, P., Gallis, M., Louka, S. F., Whiteley, M., Foulkes, B. H., Christou, S., Wolverson, P., Pohare, M., Hansford, S. E., Green, L. R., Evans, C., Raza, M., Wang, D., Gaudieri, S., Mallal, S., The COVID-19 Genomics UK (COG-UK) consortium, , de Silva, T. I.
10.1101/2021.03.02.433156 — Posted: 2021-03-03
Low-dose lung radiotherapy for COVID-19 lung disease: a pre-clinical efficacy study in a bleomycin model of pneumonitis.
Jackson, M. R., Stevenson, K., Chahal, S. K., Curley, E., Finney, G., Gutierrez-Quintana, R., Onwubiko, E., Rupp, A. F., Strathdee, K., MacLeod, M. K., McSharry, C., Chalmers, A. J.
10.1101/2021.03.03.433704 — Posted: 2021-03-03
Neutralizing IFNL3 Autoantibodies in Severe COVID-19 Identified Using Molecular Indexing of Proteins by Self-Assembly
Credle, J. J., Gunn, J., Sangkhapreecha, P., Monaco, D. R., Zheng, X. A., Tsai, H.-J., Wilbon, A., Morgenlander, W. R., Dong, Y., Jayaraman, S., Tosi, L., Parekkadan, B., Baer, A. N., Roederer, M., Bloch, E. M., Tobian, A. A. R., Zyskind, I., Silverberg, J. I., Rosenberg, A. Z., Cox, A. L., Lloyd, T., Mammen, A. L., Larman, H. B.
10.1101/2021.03.02.432977 — Posted: 2021-03-03
Blockade of SARS-CoV-2 infection in-vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor
Acharya, A., Pandey, K., Thurman, M., Challagundla, K. B., Vann, K. R., Kutateladze, T. G., Morales, G. A., Durden, D. L., Byrareddy, S. N.
10.1101/2021.03.02.433604 — Posted: 2021-03-03
A pharmacophore model for SARS-CoV-2 3CLpro small molecule inhibitors and in vitro experimental validation of computationally screened inhibitors
Glaab, E., Manoharan, G. B., Abankwa, D.
10.1101/2021.03.02.433618 — Posted: 2021-03-03
Impact of COVID-19 pandemic on Black, Asian and Minority Ethnic (BAME) communities: a qualitative study on the perspectives of BAME community leaders
Mahmood, F., Acharya, D., Kumar, K., Paudyal, V.
10.1101/2021.03.03.21252286 — Posted: 2021-03-03

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).